Evidence map›Paper›PMID 39308156›Full record

ReviewMultiple sclerosis (Houndmills, Basingstoke, England)2024

Integrating large language models in care, research, and education in multiple sclerosis management.

Hernan Inojosa, Isabel Voigt, Judith Wenk, Dyke Ferber, Isabella Wiest, Dario Antweiler, Eva Weicken, Stephen Gilbert, Jakob Nikolas Kather, Katja Akgün and 1 more

Abstract readReview
In one paragraph

Review in Multiple sclerosis (Houndmills, Basingstoke, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Mechanistic Insights into the Role of Artificial Intelligence and Machine Learning in the Diagnosis and Management of Multiple Sclerosis.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  3. Managing maternity: Moving care, not patients, using artificial intelligence (AI), internet-of-things (IOT) and point-of-care testing (POCT) devices.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  4. Detecting progressing events in multiple sclerosis clinics in real-time is possible: No.Multiple sclerosis (Houndmills, Basingstoke, England) · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hernan InojosaCenter of Clinical Neuroscience, Department of Neurology, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, Dresden, Germany.ORCID 0000-0002-1377-836X
Isabel VoigtCenter of Clinical Neuroscience, Department of Neurology, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, Dresden, Germany.
Judith WenkCenter of Clinical Neuroscience, Department of Neurology, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, Dresden, Germany.
Dyke FerberElse Kröner Fresenius Center for Digital Health, Technical University Dresden, Dresden, Germany.
Isabella WiestElse Kröner Fresenius Center for Digital Health, Technical University Dresden, Dresden, Germany.ORCID 0009-0004-4848-614X
Dario AntweilerFraunhofer Institute for Intelligent Analysis and Information Systems, Sankt Augustin, Germany.ORCID 0000-0002-2238-9753
Eva WeickenElse Kröner Fresenius Center for Digital Health, Technical University Dresden, Dresden, Germany.
Stephen GilbertElse Kröner Fresenius Center for Digital Health, Technical University Dresden, Dresden, Germany.
Jakob Nikolas KatherElse Kröner Fresenius Center for Digital Health, Technical University Dresden, Dresden, Germany.
Katja AkgünCenter of Clinical Neuroscience, Department of Neurology, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, Dresden, Germany.
Tjalf ZiemssenCenter of Clinical Neuroscience, Department of Neurology, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Use of techniques derived from generative artificial intelligence (AI), specifically large language models (LLMs), offer a transformative potential on the management of multiple sclerosis (MS). Recent LLMs have exhibited remarkable skills in producing and understanding human-like texts. The integration of AI in imaging applications and the deployment of foundation models for the classification and prognosis of disease course, including disability progression and even therapy response, have received considerable attention. However, the use of LLMs within the context of MS remains relatively underexplored. LLMs have the potential to support several activities related to MS management. Clinical decision support systems could help selecting proper disease-modifying therapies; AI-based tools could leverage unstructured real-world data for research or virtual tutors may provide adaptive education materials for neurologists and people with MS in the foreseeable future. In this focused review, we explore practical applications of LLMs across the continuum of MS management as an initial scope for future analyses, reflecting on regulatory hurdles and the indispensable role of human supervision.

Indexed as

Artificial IntelligenceMultiple SclerosisDecision Support Systems, ClinicalDisease ManagementHumansapplicationsartificial intelligencedisease managementlarge language models (LLMs)Multiple sclerosis

Identifiers

PMID39308156
PMCPMC11514324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.