Evidence map›Paper›PMID 39307901›Full record

ArticleLung2024

Factors Associated with Corticosteroid Adherence in Sarcoidosis.

Marc A Judson, Wende Ouedraogo Ouedraogo, Kenneth M Fish, Robert DeLuca, Rachel VanCavage, Krishnaveni Sirigaddi, Recai Yucel

Abstract read
PubMed Publisher
In one paragraph

Article in Lung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. New Therapies for Sarcoidosis: Molecular and Pathophysiological Basis.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marc A JudsonDepartment of Medicine, Albany Medical Center, Albany, NY, USA. judsonm@amc.edu.ORCID 0000-0002-4663-7985
Wende Ouedraogo OuedraogoDepartment of Epidemiology and Biostatistics, College of Public Health, Temple University, Philadelphia, PA, USA.
Kenneth M FishDepartment of Medicine, Albany Medical Center, Albany, NY, USA.
Robert DeLucaDepartment of Medicine, Albany Medical Center, Albany, NY, USA.
Rachel VanCavageDepartment of Medicine, Albany Medical Center, Albany, NY, USA.
Krishnaveni SirigaddiMemorial Health- Harrington Hospital, Southbridge, MA, USA.
Recai YucelDepartment of Epidemiology and Biostatistics, College of Public Health, Temple University, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe measured corticosteroid medication adherence (CMA) in sarcoidosis patients and analyzed if demographic and clinical factors, beliefs about medications, corticosteroid side-effects, psychosocial status, and the doctor-patient relationship were associated with corticosteroid adherence.

methodsSarcoidosis patients receiving corticosteroids were eligible to participate. CMA was measured using the Medication Adherence Response Scale-10 (MARS-10), a validated patient reported outcome measure (PRO). Data collection included patient demographics and clinical variables to assess their sarcoidosis phenotype. The patients were administered additional PROs concerning their psychosocial status, beliefs about medication use, corticosteroid side-effects and the strength of their doctor-patient relationship.

results132 patients were enrolled. Their mean prednisone dose was 9.9 ± 7.5 mg/day. 75% (99/132) were adherent with corticosteroids (MARS-10 ≥ 6) and 25% (33/132) were nonadherent (MARS-10 < 6). All demographic features, education level, and annual family income were not associated with CMA. Most clinical variables including spirometry, use of additional sarcoidosis drugs, number of organs involved with sarcoidosis were not associated with CMA. Almost all PROs including a better attitude toward medication use, less psychological issues, less corticosteroid side-effects, and a stronger doctor-patient relationship were associated with better CMA. A multi-logistic regression found that patient-doctor communication and the patient's intrinsic beliefs about the use of medications remained associated with CMA.

conclusionWe found no significant relationship between demographic or socioeconomic factors and CMA. Few clinical factors were associated with CMA. In a univariate analysis, CMA was associated with physician-doctor communication, beliefs about medication use, psychological/emotional issues, and corticosteroid side-effects. Only the first two of these factors remained associated with CMA in a multi-logistic analysis. These data suggest that CMA is heavily influenced by sarcoidosis patient beliefs about medications, and less so by patient demographics.

Indexed as

Health Knowledge, Attitudes, PracticeMedication AdherencePhysician-Patient RelationsAdrenal Cortex HormonesAdultAgedFemaleGlucocorticoidsHumansMaleMiddle AgedPatient Reported Outcome MeasuresPrednisoneSarcoidosisSarcoidosis, PulmonaryAdrenal Cortex HormonesGlucocorticoidsPrednisoneCorticosteroidsDemographicsDoctor-patient relationshipMedication adherenceSarcoidosisSpirometry

Identifiers

PMID39307901

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.