Evidence map›Paper›PMID 39307728›Full record

ArticleZhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi2024

[Selected donor CD34(+) cell boosts for salvage treatment of poor graft function following allogeneic hematopoietic stem cell transplantation in primary myelofibrosis: 3 cases report].

H X Shi, H X Liu, D L Wei, J Zhu, S Shao, Y Jiang, C Wang, C X Zhao

Abstract readCase ReportsEnglish Abstract
In one paragraph

Article in Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

H X ShiDepartment of Hematology, Shanghai Zhaxin Traditional Chinese and Western Medicine Hospital, Shanghai 200443, China.
H X LiuDepartment of Hematology, Shanghai Zhaxin Traditional Chinese and Western Medicine Hospital, Shanghai 200443, China.
D L WeiDepartment of Hematology, Shanghai Zhaxin Traditional Chinese and Western Medicine Hospital, Shanghai 200443, China.
J ZhuDepartment of Hematology, Shanghai Zhaxin Traditional Chinese and Western Medicine Hospital, Shanghai 200443, China.
S ShaoDepartment of Hematology, Shanghai Zhaxin Traditional Chinese and Western Medicine Hospital, Shanghai 200443, China.
Y JiangDepartment of Hematology, Shanghai Zhaxin Traditional Chinese and Western Medicine Hospital, Shanghai 200443, China.
C WangDepartment of Hematology, Shanghai Zhaxin Traditional Chinese and Western Medicine Hospital, Shanghai 200443, China.
C X ZhaoDepartment of Hematology, Shanghai Zhaxin Traditional Chinese and Western Medicine Hospital, Shanghai 200443, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A retrospective analysis was conducted on three patients with primary myelofibrosis who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT) at Shanghai Zhaxin Traditional Chinese and Western Medicine Hospital from 2020 to 2023. They subsequently developed poor graft function. The patients received selected donor CD34(+) cell boosts as salvage therapy. There were two male patients and one female patient, with a median age of 68 (39-69) years. The median time from allo-HSCT to the selected donor CD34(+) cell boost was 83 (56-154) days. The median infusion of selected donor CD34(+) cells was 7.67 (7.61-9.06) ×10(6)/kg, with a CD34(+) cell purity of 97.76% (96.50%-97.91%) and a recovery rate of 70% (42%-75%) . Hematological recovery was achieved in two cases. No acute GVHD was observed in any of the three patients. One case of moderate oral chronic GVHD was noted. Selected donor CD34(+) cell boosts for the treatment of poor graft function after allo-HSCT in primary myelofibrosis was effective and no severe acute or chronic GVHD was observed.

Indexed as

Antigens, CD34Hematopoietic Stem Cell TransplantationPrimary MyelofibrosisSalvage TherapyTransplantation, HomologousAdultAgedFemaleGraft vs Host DiseaseHumansMaleMiddle AgedRetrospective StudiesTissue DonorsAntigens, CD34

Identifiers

PMID39307728
PMCPMC11535553

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.