Evidence map›Paper›PMID 39307520›Full record

ArticleJournal of bone metabolism2024

Effects of Psychogenic Stress Frequency during the Growth Stage on Oxidative Stress, Organ and Bone Development.

Sangun Lee, Maho Tairabune, Yuka Nakamura, Atsunori Itagaki, Issei Sugimoto, Takumi Saito, Yoshihiko Shibukawa, Atsuko Satoh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bone metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sangun LeeAomori University of Health and Welfare Graduate School of Health Sciences, Aomori, Japan.
Maho TairabuneDepartment of Physical Therapy, Aomori University of Health and Welfare, Aomori, Japan.
Yuka NakamuraDepartment of Physical Therapy, Aomori University of Health and Welfare, Aomori, Japan.
Atsunori ItagakiDepartment of Physical Therapy, Tokyo Metropolitan University, Tokyo, Japan.
Issei SugimotoAomori University of Health and Welfare Graduate School of Health Sciences, Aomori, Japan.
Takumi SaitoAomori University of Health and Welfare Graduate School of Health Sciences, Aomori, Japan.
Yoshihiko ShibukawaAomori University of Health and Welfare Graduate School of Health Sciences, Aomori, Japan.
Atsuko SatohFaculty of Nursing, Hirosaki Gakuin University, Aomori, Japan.

Funding

Aomori University of health and welfare AUHW-2020-22
6 · The paper itself

Abstract

backgroundThis study aimed to examine the effects of psychogenic stress (PS) frequency on oxidative stress and organ development during growth and to gain fundamental insights into developmental processes during this period.

methodsFour-week-old male Wistar rats were randomly assigned to a control and three PS groups according to PS frequencies. PS was induced using restraint and water immersion techniques once daily for 3 hr at a time for a period of 4 weeks.

resultsOxidative stress increased with increasing PS frequency. The weights of organs other than the adrenal glands significantly decreased with increasing PS frequency, indicating growth suppression. Furthermore, bone morphology, weight, and length significantly decreased with increasing PS frequency.

conclusionsHigh-frequency PS exposure during developmental growth significantly negatively affects oxidative stress and organ and bone development. In particular, increased oxidative stress due to excessive PS has detrimental effects on organ and bone growth.

Indexed as

Bone developmentOxidative stressStress, psychological

Identifiers

PMID39307520
PMCPMC11416881

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.