Evidence map›Paper›PMID 39307437›Full record

ArticleTransplant immunology2024

Structural social determinants of health as barriers to liver transplant waitlisting.

Britney Sun, Sasha Deutsch-Link, Marina Serper

Abstract read
In one paragraph

Article in Transplant immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Britney SunNorthwestern University Feinberg School of Medicine, Chicago, IL, USA. Electronic address: britney.c.sun@wustl.edu.
Sasha Deutsch-LinkDivision of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Marina SerperDepartment of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

Funding

DIGESTIVE DISEASES EPIDEMIOLOGY TRAINING PROGRAMT32DK007634 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT S. SANDLER · 1990 to 2026
$7.4M
Developing technology-based approaches to improve access and quality of care in cirrhosisK23DK115897 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI SERPER, MARINA · 2018 to 2022
$961k
NIDDK NIH HHS K23 DK115897NIDDK NIH HHS T32 DK007634
6 · The paper itself

Abstract

Social determinants of health, both individual and structural, impact access to liver transplantation (LT). We aimed to evaluate the association between structural social determinants of health (SSDoH) and individual-level psychosocial factors (as measured by the Stanford Integrated Psychosocial Assessment for Transplant, SIPAT score) on failure to waitlist for LT. We conducted a single-center retrospective cohort study of 2762 patients evaluated for LT. SSDoH exposures included the Social Deprivation Index (SDI), the proportion of households on cash public assistance or supplemental nutrition assistance (% public assistance), and distance to the transplant center. Neighborhood SDI score in the highest quartile (OR 1.32, 95 % CI 1.07-1.63) and % on public assistance in the highest quartile (OR 1.41, 95 % CI 1.14-1.75) were associated with increased odds of not being waitlisted for LT. These associations remained significant after adjusting for individual psychosocial risk using SIPAT scores (≥21, high psychosocial risk). Highest quartile neighborhood SDI (OR 1.70, 95 % CI 1.13-2.54) and the highest quartile of % on public assistance (OR 1.67, 95 % CI 1.11-2.53) were also associated with increased odds of failure to waitlist for psychosocial reasons. However, these associations were no longer significant after adjusting for individual SIPAT scores. High-risk SIPAT scores were more prevalent in neighborhoods with the highest quartile of SSDoH measures. Transplant centers can design initiatives to build individual psychosocial support to mitigate the impact of structural barriers.

Indexed as

Liver TransplantationSocial Determinants of HealthWaiting ListsAdultAgedFemaleHealth Services AccessibilityHumansMaleMiddle AgedRetrospective StudiesLiver transplantation (LT)Social determinants of healthStanford integrated psychosocial assessment for transplant (SIPAT)

Identifiers

PMID39307437
PMCPMC11606764

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.