Evidence map›Paper›PMID 39307098›Full record

ArticleVirology2024

Depletion of monocytic myeloid-derived suppressor cells in LP-BM5 murine retroviral infection has a positive impact on virus-induced host immunodeficiency.

Kathy A Green, Chi Ma, Fukun W Hoffmann, Peter R Hoffmann, William R Green

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kathy A GreenGeisel School of Medicine at Dartmouth, Lebanon, NH, 03756, USA. Electronic address: Kathyloisann@gmail.com.
Chi MaJohn A. Burns School of Medicine, University of Hawaii, Honolulu, HI, 96813, USA.
Fukun W HoffmannJohn A. Burns School of Medicine, University of Hawaii, Honolulu, HI, 96813, USA.
Peter R HoffmannJohn A. Burns School of Medicine, University of Hawaii, Honolulu, HI, 96813, USA.
William R GreenGeisel School of Medicine at Dartmouth, Lebanon, NH, 03756, USA.

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
UH Hilo COP A&RP20GM103466 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI HELEN C TURNER · 2012 to 2026
$60.3M
The Pathogenesis of MAIDS and Specific T Cell ResponsesR01CA050157 · NCI · DARTMOUTH COLLEGE · PI GREEN, WILLIAM R · 1990 to 2009
$2.6M
The Role of Selenoprotein I in Phospholipidethanolamine Dependent Mechanisms that Regulate T Cell ActivationR01AI147496 · NIAID · UNIVERSITY OF HAWAII AT MANOA · PI HOFFMANN, PETER R · 2019 to 2023
$2.1M
NCI NIH HHS P30 CA023108NCI NIH HHS R01 CA050157NIAID NIH HHS R01 AI147496NIGMS NIH HHS P20 GM103466NIH HHS R01AAI147496
6 · The paper itself

Abstract

We have shown the induction of CD11b

Indexed as

FluorouracilMyeloid-Derived Suppressor CellsRetroviridae InfectionsAnimalsB-LymphocytesMiceMice, Inbred C57BLMonocytesRetroviridaeViral LoadFluorouracil5-FluorouracilApoptosisCD4(+) T cellsCD8(+) T cellsImmunodeficiencyMurine retrovirus LP-BM5Myeloid-derived suppressor cells

Identifiers

PMID39307098
PMCPMC11560480

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.