Evidence map›Paper›PMID 39307071›Full record

Trial reportThe journal of nutrition, health & aging2024

Daily supplementation of lesser mealworm protein for 11-weeks increases skeletal muscle mass in physically active older adults.

Lotte Koopmans, Marcia Spoelder, Coen C W G Bongers, Thijs M H Eijsvogels, Maria T E Hopman

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The journal of nutrition, health & aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Nutrition for healthy longevity: the past, the present and the future.The journal of nutrition, health & aging · 2026
    Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lotte KoopmansDepartment of Medical BioSciences, Integrative and Exercise Physiology Research Groups, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: lotte.koopmans@radboudumc.nl.
Marcia SpoelderDepartment of Medical BioSciences, Integrative and Exercise Physiology Research Groups, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Primary and Community Care, Radboud University Medical Center, Nijmegen, the Netherlands.
Coen C W G BongersDepartment of Medical BioSciences, Integrative and Exercise Physiology Research Groups, Radboud University Medical Center, Nijmegen, the Netherlands; School of Sport and Exercise, HAN University of Applied Sciences, Nijmegen, the Netherlands.
Thijs M H EijsvogelsDepartment of Medical BioSciences, Integrative and Exercise Physiology Research Groups, Radboud University Medical Center, Nijmegen, the Netherlands.
Maria T E HopmanDepartment of Medical BioSciences, Integrative and Exercise Physiology Research Groups, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: maria.hopman@radboudumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdequate protein intake is important to maintain skeletal muscle mass in older adults and to prevent sarcopenia. Insect-based supplements were recently introduced to the market as an environmentally friendly protein alternative. We examined the effect of daily supplementation of lesser mealworm (Alphitobius diaperinus) protein for 11 consecutive weeks on muscle mass and muscle strength in older adults.

methodsIn this randomized controlled trial, 70 physically active older adults (>60 years) were randomly allocated to three groups: (I) lesser mealworm protein, (II) whey protein or (III) iso-caloric placebo. Participants received 11 weeks of supplements two times a day (30 gram/day). Muscle mass, fat mass, leg muscle strength and handgrip strength were measured at baseline and after 11 weeks of supplementation.

resultsOf the 70 participants, 59 completed the supplementation period (mealworm n = 16; whey n = 23; iso-caloric placebo n = 20). Overall, skeletal muscle mass increased from 29.0 ± 6.2 kg to 29.3 ± 6.1 kg, with a significantly more profound increase in the lesser mealworm group (+0.67 [0.20-1.14] kg) compared to the whey (+0.03 [-0.20 - 0.28] kg) and placebo group (+0.30 [0.03 - 0.63] kg, P

Indexed as

Dietary SupplementsHand StrengthMuscle, SkeletalWhey ProteinsAgedAnimalsDietary ProteinsDouble-Blind MethodFemaleHumansInsect ProteinsMaleMiddle AgedMuscle StrengthSarcopeniaDietary ProteinsInsect ProteinsWhey ProteinsAlphitobius diaperinusBody compositionElderlyInsectSarcopenia

Identifiers

PMID39307071
PMCPMC12879208

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.