Evidence map›Paper›PMID 39306627›Full record

ArticleInternational ophthalmology2024

Effect of upper eyelid blepharoplasty surgery on cornea biomechanics and ocular surface.

Menekşe İnal Özen, Gülizar Demirok, Züleyha Yalnız Akkaya, Fatma Akbaş Kocaoğlu, Yasemin Katırcıoğlu, Tuba Çelik, Firdevs Örnek, Dudu Deniz Açar

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In one paragraph

Article in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07003308 (Comparative Study of the Efficacy of Anterior Versus Posterior White Line Advancement Technique in the Correction of Primary Aponeurotic Ptosis), which is not on this map. Not yet cited in PubMed.

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07003308 narecruitingnot on this mapstarted 2025, after this paper: background citation

Comparative Study of the Efficacy of Anterior Versus Posterior White Line Advancement Technique in the Correction of Primary Aponeurotic Ptosis

TypeinterventionalSponsorInstituto de Investigación Sanitaria de la Fundación Jiménez DíazRan2025 to 2027Enrolled54ConditionsPtosis, EyelidArmsAnterior White Line Advancement Surgery, Posterior White Line Advancement Surgery
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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Menekşe İnal ÖzenKastamonu Training and Research Hospital, Kastamonu, Turkey. menekse-inal-107@hotmail.com.
Gülizar DemirokAnkara Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Züleyha Yalnız AkkayaAnkara Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Fatma Akbaş KocaoğluAnkara Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Yasemin KatırcıoğluAnkara Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Tuba ÇelikAnkara Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Firdevs ÖrnekAnkara Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Dudu Deniz AçarAnkara Training and Research Hospital, University of Health Sciences, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the changes in corneal biomechanical properties and tear film layer analysis after upper eyelid blepharoplasty surgery.

methodSixty eyes of 30 patients were included in our prospective study. Corneal hysteresis (CH), corneal resistance factor (CRF), corneal compensated intraocular pressure (IOPcc) and Goldmann intraocular pressure (IOPg) measurements were taken with the Ocular Response Analyzer (ORA) device at the preoperative, postoperative 1st and 3rd months. The ocular surface was evaluated with tear breakup time (TBUT) and Ocular Surface Disease Index (OSDI) scores. Lid crease (LC), margin-to-reflex distance 1 (MRD1), and palpebral fissure height (PFH) were evaluated at each visit.

resultsIn the ORA analysis, in the 1st month CH value was found to be significantly lower than the preoperative value (preoperative 13.39 ± 6.08 mmHg; 1st month 10.74 ± 1.94 mmHg, p = 0.011). In addition, there was a statistically significant decrease in the 3rd month value compared to the preoperative values (10.46 ± 1.69 mmHg, p = 0.021). However CRF decreased postoperatively, no statistical difference was detected (preop 12.59 ± 3.84; 1st month 11.94 ± 3.04; 3rd month 9.78 ± 1.74; p = 0.149). While there was a decrease in IOPcc and IOPg in the postoperative period, no statistical difference was detected (respectively p = 0.96, p = 0.71). In the postoperative 1st month, TBUT increased significantly (p = 0.024). When those with a TBUT value below 10 were considered dry eye, significant decrease was observed in the percentage of dry eye in the first postoperative month (p = 0.027). Although the dry eye percentage decreased in the 3rd month compared to the preoperative percentage, no statistical difference was detected (p = 0.125). There was a significant decrease in the number of those with an OSDI score above 13 in the first month (p = 0.004).

conclusionIn our study, a decrease in ORA values was observed after blepharoplasty, with only CH being statistically significant. Reducing the load on the cornea after surgery may change the corneal biomechanics. These changes should be taken into consideration after eyelid surgery, especially in patients who may require glaucoma follow-ups.

Indexed as

BlepharoplastyCorneaEyelidsIntraocular PressureTearsAdultAgedBiomechanical PhenomenaElasticityFemaleFollow-Up StudiesHumansMaleMiddle AgedPostoperative PeriodProspective StudiesBlepharoplastyCorneal hysteresisCorneal resistance factorOcular response analyzerOcular surface disease ındexTear break-up time

Identifiers

PMID39306627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.