ArticleDevelopmental cell2024
DRMY1 promotes robust morphogenesis in Arabidopsis by sustaining the translation of cytokinin-signaling inhibitor proteins.
Article in Developmental cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed.
- ROS inhibits microtubule dynamics and cell growth heterogeneity during Arabidopsis sepal morphogenesis.iScience · 2026Article
- Spatial and single-cell transcriptomics uncover brassinosteroid-mediated coordination of sepal elongation in Arabidopsis.Genome biology · 2026Article
- Translational control in plants: from basic mechanisms to environmental and developmental responses.The Plant journal : for cell and molecular biology · 2026Review
- Nutrient-driven TOR signalling controls a chromatin-associated complex for orchestrating plant growth and stress tolerance.Nature plants · 2025Article
- Brassinosteroids mediate proper coordination of sepal elongation.bioRxiv : the preprint server for biology · 2025Article
- Stochastic gene expression in auxin signaling in the floral meristem of Arabidopsis thaliana.Nature communications · 2025Article
- A space for time. Exploring temporal regulation of plant development across spatial scales.The Plant journal : for cell and molecular biology · 2025Review
- Robust organ size in Arabidopsis is primarily governed by cell growth rather than cell division patterns.Development (Cambridge, England) · 2024Article
- Tradeoff between speed and robustness in primordium initiation mediated by auxin-CUC1 interaction.Nature communications · 2024Article
- Tradeoff Between Speed and Robustness in Primordium Initiation Mediated by Auxin-CUC1 Interaction.bioRxiv : the preprint server for biology · 2024Article
- Communicating Across Cell Walls: Structure, Evolution, and Regulation of Plasmodesmatal Transport in Plants.Results and problems in cell differentiation · 2024Review
- Robust organ size in Arabidopsis is primarily governed by cell growth rather than cell division patterns.bioRxiv : the preprint server for biology · 2023Article
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Abstract
Robustness is the invariant development of phenotype despite environmental changes and genetic perturbations. In the Arabidopsis flower bud, four sepals robustly initiate and grow to a constant size to enclose and protect the inner floral organs. We previously characterized the mutant development-related myb-like 1 (drmy1), where 3-5 sepals initiate variably and grow to different sizes, compromising their protective function. The molecular mechanism underlying this loss of robustness was unclear. Here, we show that drmy1 has reduced TARGET OF RAPAMYCIN (TOR) activity, ribosomal content, and translation. Translation reduction decreases the protein level of ARABIDOPSIS RESPONSE REGULATOR7 (ARR7) and ARABIDOPSIS HISTIDINE PHOSPHOTRANSFER PROTEIN 6 (AHP6), two cytokinin-signaling inhibitors that are normally rapidly produced before sepal initiation. The resultant upregulation of cytokinin signaling disrupts robust auxin patterning and sepal initiation. Our work shows that the homeostasis of translation, a ubiquitous cellular process, is crucial for the robust spatiotemporal patterning of organogenesis.
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