Evidence map›Paper›PMID 39305397›Full record

ArticleClinical & experimental metastasis2024

Multi-marker analysis of circulating tumor cells in localized intermediate/high-risk and metastatic prostate cancer.

Eva Welsch, Lilli Bonstingl, Barbara Holzer, Eva Schuster, Esther Weiß, Alexandru-Teodor Zaharie, Michael Krainer, Michael B Fischer, Amin El-Heliebi, Robert Zeillinger and 1 more

Abstract read
In one paragraph

Article in Clinical & experimental metastasis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Biomarkers in Localized Prostate Cancer: From Diagnosis to Treatment.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eva WelschMolecular Oncology Group, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel 18-20, Vienna, 1090, Austria.ORCID 0009-0008-3560-1769
Lilli BonstinglDivision of Cell Biology, Histology and Embryology, Gottfried Schatz Research Centre, Medical University of Graz, Graz, Austria.ORCID 0009-0009-0757-6962
Barbara HolzerMolecular Oncology Group, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel 18-20, Vienna, 1090, Austria.
Eva SchusterMolecular Oncology Group, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel 18-20, Vienna, 1090, Austria.
Esther WeißOncoLab Diagnostics GmbH, Wiener Neustadt, Austria.ORCID 0000-0002-9187-8358
Alexandru-Teodor ZaharieDepartment of Radiation Oncology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-8697-9058
Michael KrainerDivision of Oncology, Department for Medicine I, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-7011-4957
Michael B FischerDepartment of Blood Group Serology and Transfusion Medicine, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-5876-0243
Amin El-HeliebiDivision of Cell Biology, Histology and Embryology, Gottfried Schatz Research Centre, Medical University of Graz, Graz, Austria.ORCID 0000-0002-7679-6856
Robert ZeillingerMolecular Oncology Group, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel 18-20, Vienna, 1090, Austria.ORCID 0000-0001-6771-4591
Eva ObermayrMolecular Oncology Group, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel 18-20, Vienna, 1090, Austria. eva.obermayr@muv.ac.at.ORCID 0000-0001-6324-2961

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circulating tumor cells (CTCs) are an established prognostic marker in metastatic prostate cancer (PrC) but have received little attention in localized high-risk disease. Peripheral blood was obtained from patients with early intermediate and high-risk PrC (n = 15) at baseline, after radiotherapy, and during follow-up, as well as from metastatic PrC patients (n = 23). CTCs were enriched using the microfluidic Parsortix

Indexed as

Biomarkers, TumorNeoplastic Cells, CirculatingProstatic NeoplasmsAgedAged, 80 and overAntigens, SurfaceFollow-Up StudiesGlutamate Carboxypeptidase IIHumansIn Situ HybridizationMaleMiddle AgedNeoplasm MetastasisPrognosisProstate-Specific AntigenAntigens, SurfaceBiomarkers, TumorFOLH1 protein, humanGlutamate Carboxypeptidase IIProstate-Specific AntigenCirculating tumor cellsGene expressionLiquid biopsyParsortixProstate cancerqPCR

Identifiers

PMID39305397
PMCPMC11607046

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.