ArticleJournal of assisted reproduction and genetics2024
Factors associated with decision outcomes along the planned oocyte cryopreservation pathway in a cohort of women who sought consultation before and during the COVID-19 pandemic.
Article in Journal of assisted reproduction and genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
purposeTo identify factors associated with three decision outcomes along the planned oocyte cryopreservation (POC) pathway: fertility assessment completion, POC uptake, and multiple POC cycles uptake.
methodsA single-site retrospective cohort study of 425 patients who sought POC consultation from 2018-2022 before and during the COVID-19 pandemic.
resultsThe mean age of patients at consultation was 35.2 ± 4.0. 73% (n = 310) of the new consultations occurred since the COVID-19 pandemic. 335 patients completed fertility assessment following consultation. Of the 335 patients (78.8%) completing fertility assessment, 139 (32.7%) underwent at least one cycle. The odds of completing fertility assessment were 3.65 times greater for patients being seen pre-pandemic than for those being seen during the pandemic (p < 0.001). Not having a committed partner (OR 2.61, p < 0.001) and not having a prior pregnancy history (OR 1.99, p = 0.03) positively predicted POC uptake. Each additional number of cryopreserved MII oocytes in the first cycle reduced the odds of undergoing more cycles by 0.74 times (p < 0.001). Of the 196 patients with no POC uptake despite having a fertility consultation, 10 decided to do nothing, 16 decided to get pregnant with or without a partner, and the other 170 had not yet indicated their decision.
conclusionOur centre experienced a surge of patients seeking POC consultation since the COVID-19 outbreak. Approximately one-third of these patients progressed to the POC stage. Our findings validate the complexity of POC decision-making and the value of providing ongoing decision support to patients along the POC pathway.
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