Evidence map›Paper›PMID 39305358›Full record

ArticleOdontology2025

Evaluation of the systemic effect of bone formation marker released by endodontic calcium silicate-based sealers in local tissues, the bloodstream, and body organs.

Índia Olinta De Azevedo Queiroz, Wagner Garcez de Mello, Thiago Machado, Maria Carolina Guiotti de Oliveira, Bruno Carvalho Vasconcelos, Sandra Helena Penha de Oliveira, Marco Antonio Hungaro Duarte

Abstract read
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Article in Odontology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Índia Olinta De Azevedo QueirozDepartment of Dentistry, Federal University of Santa Catarina, UFSC, Florianópolis, Santa Catarina, Brazil. india.queiroz@ufsc.br.ORCID http://orcid.org/0000-0001-8214-0880
Wagner Garcez de MelloDepartment of Basic Science, Araçatuba Dental School, UNESP, Araçatuba, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-8236-5171
Thiago MachadoDepartment of Oral and Maxillofacial Surgery and Integrated Clinic, Araçatuba Dental School, UNESP, Araçatuba, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-6154-7195
Maria Carolina Guiotti de OliveiraDepartment of Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, USP, Bauru, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-0073-005X
Bruno Carvalho VasconcelosDepartment of Dentistry Campos Sobral, Federal University of Ceará, UFC, Sobral, Ceará, Brazil.ORCID http://orcid.org/0000-0003-4415-5680
Sandra Helena Penha de OliveiraDepartment of Basic Science, Araçatuba Dental School, UNESP, Araçatuba, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-0805-1120
Marco Antonio Hungaro DuarteDepartment of Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, USP, Bauru, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-3051-737X

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 30358/2016-4
6 · The paper itself

Abstract

Calcium silicate-based sealers are bioactive materials that release ions when in contact with body fluids. Therefore, this study aims mapping/trace bone formation markers released by MTA Fillapex, BioRoot RCS, and experimental tricalcium silicate-based sealer (CEO) into subcutaneous tissues, bloodstream and body organs. Toward, polyethylene tubes filled with sealers were implanted into connective tissue of Wistar rats. On days 7, 15, 30, and 45 after implantation, blood samples were collected to measure calcium (Ca

Indexed as

Calcium CompoundsOsteogenesisRoot Canal Filling MaterialsSilicatesAlkaline PhosphataseAluminum CompoundsAnimalsBiomarkersCalciumDrug CombinationsMaleOxidesPhosphorusRatsRats, WistarAlkaline PhosphataseAluminum CompoundsBiomarkersCalciumCalcium Compoundscalcium silicateDrug Combinationsmineral trioxide aggregateOxidesPhosphorusRoot Canal Filling MaterialsSilicatestricalcium silicateBody organsBone markersCalcium silicateRoot canal filling

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.