Evidence map›Paper›PMID 39305272›Full record

ReviewGut microbes

A new perspective in intestinal microecology: lifting the veil of exercise regulation of cardiometabolic diseases.

Can Gao, Jinwen Wei, Changxu Lu, Lijie Wang, Dan Dong, Mingli Sun

Abstract readReview
In one paragraph

Review in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Can GaoCollege of Exercise and Health, Shenyang Sport University, Shenyang, Liaoning, P. R. China.
Jinwen WeiCollege of Exercise and Health, Shenyang Sport University, Shenyang, Liaoning, P. R. China.
Changxu LuCollege of Exercise and Health, Shenyang Sport University, Shenyang, Liaoning, P. R. China.
Lijie WangDepartment of Cardiology, The Fourth Affiliated Hospital of China Medical University, Shenyang, Liaoning, P. R. China.
Dan DongCollege of Basic Medical Science, China Medical University, Shenyang, Liaoning, P. R. China.
Mingli SunCollege of Exercise and Health, Shenyang Sport University, Shenyang, Liaoning, P. R. China.ORCID 0009-0001-3164-2546

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiometabolic diseases (CMDs), encompassing cardiovascular and metabolic dysfunctions, characterized by insulin resistance, dyslipidemia, hepatic steatosis, and inflammation, have been identified with boosting morbidity and mortality due to the dearth of efficacious therapeutic interventions. In recent years, studies have shown that variations in gut microbiota and its own metabolites can influence the occurrence of CMDs. Intriguingly, the composition and function of the gut microbiota are susceptible to exercise patterns, thus affecting inflammatory, immune, and metabolic responses within the host. In this review, we introduce the key mechanisms of intestinal microecology involved in the onset and development of CMDs, discuss the relationship between exercise and intestinal microecology, and then analyze the role of intestinal microecology in the beneficial effects of exercise on CMDs, aiming at elucidating the gut-heart axis mechanisms of exercise mediated protective effect on CMDs, building avenues for the application of exercise in the management of CMDs.

Indexed as

Cardiovascular DiseasesExerciseGastrointestinal MicrobiomeAnimalsHumansIntestinesMetabolic Diseasescardiometabolic diseasesExercisegut microbiotaintestinal barrier functionintestinal microecology

Identifiers

PMID39305272
PMCPMC11418258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.