Evidence map›Paper›PMID 39305192›Full record

ArticleNeurocase2024

Socioemotional dysfunction and the greater good: a case study.

Rea Antoniou, Patrick Callahan, Joel H Kramer, Bruce L Miller, Winston Chiong, Katherine P Rankin

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurocase, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rea AntoniouMemory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, CA, USA.
Patrick CallahanMemory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, CA, USA.
Joel H KramerMemory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, CA, USA.
Bruce L MillerMemory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-0875-2103
Winston ChiongMemory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, CA, USA.
Katherine P RankinMemory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, CA, USA.

Funding

TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2M
Measuring Altered Social Behavior in Neurodegenerative DiseaseR01AG029577 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RANKIN, KATHERINE P · 2008 to 2018
$3.6M
Neuroanatomy of social Function in FTDK23AG021606 · NIA · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI RANKIN, KATHERINE P · 2003 to 2005
$204k
NIA NIH HHS K23 AG021606NIA NIH HHS P01 AG019724NIA NIH HHS R01 AG029577
6 · The paper itself

Abstract

Moral cognition has largely been studied via dilemmas in which making a utilitarian choice causes instrumental harm (negative dimension). Studies of utilitarianism link this behavior with socioemotional unresponsiveness. However, there is a positive dimension of utilitarianism in which one sacrifices the good of oneself or close others for the overall welfare. We measured utilitarian choices multidimensionally in a patient with behavioral variant frontotemporal dementia (bvFTD), incorporating dilemmas accounting for negative and positive dimensions. Despite socioemotional deficits our patient was highly utilitarian in the positive, dimension of utilitarianism. This case study challenges the tendency to automatically associate bvFTD with antisocial tendencies.

Indexed as

Frontotemporal DementiaEmotionsHumansMoralsbvFTDcase studyimpartial choicesMoral cognitionsocioemotional responsiveness

Identifiers

PMID39305192
PMCPMC11604522

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.