Evidence map›Paper›PMID 39305042›Full record

ArticleMolecular microbiology2024

Analysis of bb0556 Expression and Its Role During Borrelia burgdorferi Mammalian Infection.

Sierra George, Connor Waldron, Christina Thompson, Zhiming Ouyang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Infection and immunity · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sierra GeorgeDepartment of Molecular Medicine, University of South Florida, Tampa, Florida, USA.
Connor WaldronDepartment of Molecular Medicine, University of South Florida, Tampa, Florida, USA.
Christina ThompsonDepartment of Molecular Medicine, University of South Florida, Tampa, Florida, USA.
Zhiming OuyangDepartment of Molecular Medicine, University of South Florida, Tampa, Florida, USA.ORCID 0000-0001-7427-1856

Funding

Virulence regulation by BadR in the Lyme disease spirocheteR01AI152983 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI OUYANG, ZHIMING · 2021 to 2025
$1.9M
Analysis of the DksA regulon in the Lyme disease spirocheteR21AI159061 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI OUYANG, ZHIMING · 2021 to 2022
$411k
Virulence-associated genes in the Lyme disease spirocheteR03AI146909 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI OUYANG, ZHIMING · 2019 to 2020
$150k
NIAID NIH HHS R01 AI152983NIAID NIH HHS R03 AI146909NIAID NIH HHS R21 AI159061NIH HHS AI146909NIH HHS AI152983NIH HHS AI159061
6 · The paper itself

Abstract

In Borrelia burgdorferi, BB0556 was annotated as a conserved hypothetical protein. We herein investigated gene expression and the importance of this protein during infection. Our data support that bb0556 forms an operon with five other genes. A transcriptional start site and the associated σ

Indexed as

Bacterial ProteinsBorrelia burgdorferiGene Expression Regulation, BacterialLyme DiseaseOperonPromoter Regions, GeneticAnimalsMiceTranscription Initiation SiteVirulenceBacterial ProteinsBorrelia burgdorferiLyme diseasepathogenesisvirulence

Identifiers

PMID39305042
PMCPMC11659052

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.