Evidence map›Paper›PMID 39304851›Full record

ArticleBMC veterinary research2024

Effects of inactivated Lactobacillus rhamnosus on growth performance, serum indicators, and colonic microbiota and metabolism of weaned piglets.

Zhiheng Shu, Junhao Zhang, Qingwen Zhou, Yingjie Peng, Yuanhao Huang, Yi Zhou, Jun Zheng, Manya Zhao, Chao Hu, Shile Lan

Abstract read
In one paragraph

Article in BMC veterinary research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. The Effects ofMicroorganisms · 2026
    Article
  2. Article
  3. Effects of inactivatedAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
    Article
  4. Dietary Supplementation ofAnimals : an open access journal from MDPI · 2025
    Article
  5. Sheep-DerivedMicroorganisms · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhiheng ShuCollege of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, 410128, China.
Junhao ZhangCollege of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, 410128, China.
Qingwen ZhouCollege of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, 410128, China.
Yingjie PengGuangdong Chuangzhan Bona Agricultural Technology Co., Ltd, Guangning, 526339, China.
Yuanhao HuangCollege of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, 410128, China.
Yi ZhouCollege of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, 410128, China.
Jun ZhengCollege of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, 410128, China.
Manya ZhaoCollege of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, 410128, China.
Chao HuCollege of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, 410128, China. 546092186@qq.com.
Shile LanCollege of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, 410128, China. lans2016@hunau.edu.cn.

Funding

Hunan Provincial Natural Science Foundation 2021JJ50130Special Fund for the Construction of Innovative Provinces in Hunan Province 2020NK2029
6 · The paper itself

Abstract

backgroundTo assess the effects of inactivated Lactobacillus rhamnosus (ILR) on growth performance, serum biochemical indices, colonic microbiota, and metabolomics in weaned piglets, 120 piglets were randomly divided into five groups. Samples in the control group were fed a basal diet, while the experimental ILR1, ILR2, ILR3, and ILR4 groups were fed basal diets supplemented with 0.1%, 0.2%, 0.3%, and 0.4% ILR, respectively. The prefeeding period lasted for 5 days and was followed by a formal period of 28 days.

resultsCompared to the control, the average daily gain increased by 4.38%, 7.98%, 19.32%, and 18.80% for ILR1, ILR2, ILR3, and ILR4, respectively, and the ratio of feed to gain decreased by 0.63%, 3.80%, 12.66%, and 10.76%, respectively. Serum IgA, IgG, IgM, total antioxidant capacity, and glutathione peroxidase levels increased significantly in weaned piglets in the treatment groups. Addition of 0.3% ILR significantly increased the Shannon and Simpson indices of the colonic microbiota in weaned piglets and altered the microbiota composition. Changes in metabolic profiles were observed and were primarily related to the urea cycle, amino acid metabolism, and lipid metabolism.

conclusionILR improved growth performance and serum immunological and biochemical indices and optimized the colonic microbiota structure and metabolism of weaned piglets.

Indexed as

ColonDietGastrointestinal MicrobiomeLacticaseibacillus rhamnosusProbioticsWeaningAnimal FeedAnimalsMaleSwineColonic microbiotaInactivated lactobacillus rhamnosusMetabolomeWeaned piglets

Identifiers

PMID39304851
PMCPMC11414191

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.