Evidence map›Paper›PMID 39304811›Full record

ArticleBMC plant biology2024

Homologous mapping yielded a comprehensive predicted protein-protein interaction network for peanut (Arachis hypogaea L.).

Fangping Gong, Di Cao, Xiaojian Sun, Zhuo Li, Chengxin Qu, Yi Fan, Zenghui Cao, Kai Zhao, Kunkun Zhao, Ding Qiu and 5 more

Abstract read
In one paragraph

Article in BMC plant biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Functional Genomics: From Soybean to Legume.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Fangping Gong *College of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China.
Di Cao *College of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China.
Xiaojian SunCollege of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China.
Zhuo LiCollege of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China.
Chengxin QuCollege of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China.
Yi FanCollege of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China.
Zenghui CaoCollege of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China.
Kai ZhaoCollege of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China.
Kunkun ZhaoCollege of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China.
Ding QiuCollege of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China.
Zhongfeng LiCollege of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China.
Rui RenCollege of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China.
Xingli MaCollege of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China.
Xingguo ZhangCollege of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China.
Dongmei YinCollege of Agronomy, Henan Agricultural University, Zhengzhou, 450000, People's Republic of China. yindm@henau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProtein-protein interactions are the primary means through which proteins carry out their functions. These interactions thus have crucial roles in life activities. The wide availability of fully sequenced animal and plant genomes has facilitated establishment of relatively complete global protein interaction networks for some model species. The genomes of cultivated and wild peanut (Arachis hypogaea L.) have also been sequenced, but the functions of most of the encoded proteins remain unclear.

resultsWe here used homologous mapping of validated protein interaction data from model species to generate complete peanut protein interaction networks for A. hypogaea cv. 'Tifrunner' (282,619 pairs), A. hypogaea cv. 'Shitouqi' (256,441 pairs), A. monticola (440,470 pairs), A. duranensis (136,363 pairs), and A. ipaensis (172,813 pairs). A detailed analysis was conducted for a putative disease-resistance subnetwork in the Tifrunner network to identify candidate genes and validate functional interactions. The network suggested that DX2UEH and its interacting partners may participate in peanut resistance to bacterial wilt; this was preliminarily validated with overexpression experiments in peanut.

conclusionOur results provide valuable new information for future analyses of gene and protein functions and regulatory networks in peanut.

Indexed as

ArachisPlant ProteinsProtein Interaction MapsDisease ResistancePlant DiseasesProtein Interaction MappingPlant ProteinsBioinformatic analysisDisease-resistance proteinsPPIsProtein interactomeRalstonia solanacearum

Identifiers

PMID39304811
PMCPMC11414100

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.