Evidence map›Paper›PMID 39304589›Full record

Trial reportAIDS and behavior2024

Technology-Based Interventions, with a Stepped Care Approach, for Reducing Sexual Risk Behaviors and Increasing PrEP Initiation Among Transgender and Gender Expansive Youth and Young Adults.

Cathy J Reback, Demetria Cain, Joshua A Rusow, David Benkeser, Lindsey Schader, Bevin A Gwiazdowski, Simone J Skeen, Marissa Hannah, Marvin Belzer, Marne Castillo and 9 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in AIDS and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04000724 (TechStep), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04000724 nacompletednot on this map

TechStep: Technology-based Stepped Care to Stem Transgender Adolescent Risk Transmission

TypeinterventionalSponsorFriends Research Institute, Inc.Ran2019 to 2022Enrolled254ConditionsHIVArmsText Messaging (Text+Step), WebApp (App+Step), Information/No Step
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Cathy J RebackFriends Research Institute, Inc., Los Angeles, CA, USA.
Demetria CainDepartment of Psychology, Hunter College, City University of New York, New York, NY, USA.
Joshua A RusowFriends Research Institute, Inc., Los Angeles, CA, USA.
David BenkeserDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Lindsey SchaderDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Bevin A GwiazdowskiDivision of Adolescent Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Simone J SkeenDepartment of Social, Behavioral, and Population Sciences, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA.
Marissa HannahDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Marvin BelzerDepartment of Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Marne CastilloDivision of Adolescent Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Kenneth H MayerThe Fenway Institute and Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Mary E PaulDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Jonathan Hill-RorieThe Fenway Institute and Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Nathan Dorcey JohnsonDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Julie McAvoy-BanerjeaDepartment of Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Travis SanchezDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Lisa B Hightow-WeidmanCollege of Nursing, Florida State University, Tallahassee, FL, USA.
Patrick S SullivanDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Keith J HorvathDepartment of Psychology, San Diego State University, 6363 Alvarado Rd, Suite 250, San Diego, CA, 92120, USA. Khorvath@sdsu.edu.ORCID http://orcid.org/0000-0001-7569-2839

Funding

The UNC/Emory Center for Innovative Technology (iTech) across the prevention and care continuumU19HD089881 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HIGHTOW-WEIDMAN, LISA B, SULLIVAN, PATRICK SEAN · 2016 to 2022
$35.8M
National Institute of Child Health and Human Development 1U19HD089881NICHD NIH HHS U19 HD089881
6 · The paper itself

Abstract

TechStep was a technology-based trial, with a stepped care approach, to reduce sexual risks and increase PrEP uptake among transgender and gender expansive youth and young adults (15-24 years old). From October 2019 to September 2021, 254 participants were randomized into: 1) Text (n = 82), or 2) Webapp (n = 87), or 3) Control (n = 85). At the 3-month follow-up assessment, those randomized to Text and Webapp and did not demonstrate improvement on primary outcomes were re-randomized to receive virtual eCoaching (Text + or Webapp +), or to remain in their initial condition without eCoaching. Results showed no effect on condomless encounters at 6-month, the primary endpoint, when comparing the Webapp + (0.33 decrease; 95%CI: -0.01, 0.67, p-value = 0.057) or the Text + (0.27 decrease; 95%CI: -0.13, 0.68, p-value = 0.181) conditions to the Control condition. However, in secondary analyses, condomless encounters were significantly reduced for Text compared to Control. The rate of PrEP uptake was low for all study arms.Trial registration: Clinical Trials # NCT04000724 (registered June 26, 2019).

Indexed as

HIV InfectionsPre-Exposure ProphylaxisRisk Reduction BehaviorSexual BehaviorText MessagingTransgender PersonsAdolescentFemaleHumansMaleRisk-TakingSexual and Gender MinoritiesYoung AdultHIVmHealthPrEPTechnologyTransgender

Identifiers

PMID39304589

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.