Evidence map›Paper›PMID 39304546›Full record

SynthesisInternational journal of colorectal disease2024

Management of complications in patients with an ileostomy: an umbrella review of systematic reviews for the EndOTrial Consortium.

Virginia Solitano, Sudheer Kumar Vuyyuru, Yuhong Yuan, Siddharth Singh, Neeraj Narula, Christopher Ma, Jurij Hanzel, Megan Hutton, Julie Ann Van Koughnett, Florian Rieder and 1 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in International journal of colorectal disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Virginia SolitanoDepartment of Medicine, Division of Gastroenterology, Department of Epidemiology and Biostatistics, Western University, London, ON, Canada.
Sudheer Kumar VuyyuruDepartment of Medicine, Division of Gastroenterology, Department of Epidemiology and Biostatistics, Western University, London, ON, Canada.
Yuhong YuanDepartment of Medicine, Division of Gastroenterology, Department of Epidemiology and Biostatistics, Western University, London, ON, Canada.
Siddharth SinghDivision of Gastroenterology, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
Neeraj NarulaDepartment of Medicine, Division of Gastroenterology, Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada.
Christopher MaAlimentiv Inc, London, ON, Canada.
Jurij HanzelAlimentiv Inc, London, ON, Canada.
Megan HuttonNursing Practice Excellence and Innovation, London Health Sciences Centre, London, ON, Canada.
Julie Ann Van KoughnettDivision of General Surgery, Department of Surgery, University of Western Ontario, London, ON, Canada.
Florian RiederDepartment of Cancer Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Vipul JairathDepartment of Medicine, Division of Gastroenterology, Department of Epidemiology and Biostatistics, Western University, London, ON, Canada. vjairath@uwo.ca.

Funding

Comparative effectiveness research in Hispanic patients with inflammatory bowel diseasesR01DK135937 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Siddharth Singh · 2024 to 2026
$1.9M
NIDDK NIH HHS R01 DK135937
6 · The paper itself

Abstract

backgroundStandardized clinical care processes for patients with Crohn's disease (CD) and a permanent ileostomy (PI) are lacking. The EndOTrial consortium aims to address this gap by developing pathways for care.

methodsIn this umbrella review, we searched major databases for relevant systematic reviews (SRs) or scoping reviews (ScR) published until January 5, 2024. Screening, data extraction, and quality appraisal (AMSTAR 2) were performed by two independent reviewers.

resultsOf 1349 screened papers, 22 reviews met our inclusion criteria, including 20 SRs (eight with meta-analysis) and 2 ScRs. None exclusively focused on PI. Furthermore, nine reviews did not mention patients with inflammatory bowel disease (IBD), and only two reviews included patients with high-output ileostomy, highlighting a large evidence gap. The identified reviews covered six categories with nine types of interventions, including ostomy care pathways, peristomal skin care, patient education, clinical management of high-output stoma, management and prevention of postoperative ileus, dietary and nutritional support, nursing and supporting care, telemedicine, and self-management interventions. Most SRs including nursing interventions for stoma care highlighted nurses' role in a variety of standard and specialized treatments. Notably, none of the reviews exclusively examined disease recurrence, stoma pouching systems or adhesives, behavioral interventions, or mental health in patients living with ileostomy.

conclusionsEvidence for best practice interventions to treat complications and improve quality of life in patients living with an ileostomy for CD is limited and heterogeneous. These results outline the need for standardized clinical care processes and pathways tailored to the unique needs of this patient population.

Indexed as

IleostomyCrohn DiseaseHumansPostoperative ComplicationsSystematic Reviews as TopicIBDOstomatesStomaUmbrella

Identifiers

PMID39304546
PMCPMC11415412

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.