Evidence map›Paper›PMID 39303431›Full record

ArticleDevelopmental cognitive neuroscience2024

The importance of timing of socioeconomic disadvantage throughout development for depressive symptoms and brain structure.

Lia Ferschmann, Håkon Grydeland, Niamh MacSweeney, Dani Beck, Marieke G N Bos, Linn B Norbom, Eira R Aksnes, Mona Bekkhus, Alexandra Havdahl, Eveline A Crone and 2 more

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Article in Developmental cognitive neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Lia FerschmannPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway. Electronic address: lia.ferschmann@psykologi.uio.no.
Håkon GrydelandCenter for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Oslo, Norway.
Niamh MacSweeneyPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway; Division of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway.
Dani BeckPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway; Division of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway.
Marieke G N BosLeiden Institute for Brain and Cognition, Leiden University, Leiden, the Netherlands; Institute of Psychology, Leiden University, Leiden, the Netherlands, Leiden University, Leiden, the Netherlands.
Linn B NorbomPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.
Eira R AksnesPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway; Division of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway.
Mona BekkhusPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.
Alexandra HavdahlPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway; Center for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway; Nic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway.
Eveline A CroneErasmus School of Social and Behavioral Sciences, Erasmus University Rotterdam, Rotterdam, the Netherlands.
Tilmann von SoestPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.
Christian K TamnesPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway; Division of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway.

Funding

Medical Research Council 102215/2/13/2Medical Research Council 217065/Z/19/ZMedical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009Wellcome Trust 102215/2/13/2Wellcome Trust 217065/Z/19/Z
6 · The paper itself

Abstract

Prior studies have reported associations between socioeconomic disadvantage, brain structure and mental health outcomes, but the timing of these relations is not well understood. Using prospective longitudinal data from the Avon Longitudinal Study of Parents and Children (ALSPAC), this preregistered study examined whether socioeconomic disadvantage related differentially to depressive symptoms (n=3012-3530) and cortical and subcortical structures (n=460-733) in emerging adults, depending on the timing of exposure to socioeconomic disadvantage. Family income in early childhood and own income measured concurrently were both significantly related to depressive symptoms in emerging adulthood. Similar results were observed for perceived financial strain. In contrast, only family income in early childhood was associated with brain structure in emerging adulthood, with positive associations with intracranial volume and total and regional cortical surface area. The findings suggest that both objective and subjective aspects of one's financial standing throughout development relate to depressive symptoms in adulthood, but that specifically early life family income is related to brain structural features in emerging adulthood. This suggests that associations between socioeconomic disadvantage and brain structure originate early in neurodevelopment, highlighting the role of timing of socioeconomic disadvantage.

Indexed as

BrainDepressionAdolescentAdultChildFemaleHumansIncomeLongitudinal StudiesMagnetic Resonance ImagingMaleProspective StudiesSocioeconomic Disparities in HealthSocioeconomic FactorsYoung AdultALSPACBrain structureDepressionDevelopmentMRISocioeconomic status

Identifiers

PMID39303431
PMCPMC11439534

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.