Evidence map›Paper›PMID 39302944›Full record

ArticlePLOS global public health2024

Perceived ease of use of Truenat among laboratory staff as a new diagnostic tool for TB in Nigeria: Result of a pilot roll-out.

Austin Ihesie, Nkiru Nwokoye, Jamiu Olabamiji, Kingsley Ochei, Rupert Eneogu, Debby Nongo, Aminu Babayi, Rayi Olugbemiga, Bethrand Odume, Aderonke Agbaje and 7 more

Abstract read
In one paragraph

Article in PLOS global public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Austin IhesieHIV AIDS & TB Office, USAID Nigeria, Abuja, Nigeria.ORCID https://orcid.org/0000-0002-1739-6350
Nkiru NwokoyeKNCV Nigeria, Abuja, Nigeria.
Jamiu OlabamijiIHV-Nigeria, Lagos, Nigeria.
Kingsley OcheiUSAID Leap Project, Abuja, Nigeria.
Rupert EneoguHIV AIDS & TB Office, USAID Nigeria, Abuja, Nigeria.ORCID https://orcid.org/0000-0002-3616-7457
Debby NongoHIV AIDS & TB Office, USAID Nigeria, Abuja, Nigeria.
Aminu BabayiKNCV Nigeria, Abuja, Nigeria.
Rayi OlugbemigaIHV-Nigeria, Lagos, Nigeria.
Bethrand OdumeKNCV Nigeria, Abuja, Nigeria.
Aderonke AgbajeIHV-Nigeria, Lagos, Nigeria.
Omosalewa OyelaranHIV AIDS & TB Office, USAID Nigeria, Abuja, Nigeria.
Wayne van GermertSTOP TB Partnership, Geneva, Switzerland.
Lucy MupfumiSTOP TB Partnership, Geneva, Switzerland.ORCID https://orcid.org/0000-0002-2290-2481
Omoniyi AmosWorld Health Organization, Abuja, Nigeria.
Elom EmekaFederal Ministry of Health, Abuja, Nigeria.
Chukwuma AnyaikeFederal Ministry of Health, Abuja, Nigeria.
Edmund Ndudi OssaiDepartment of Community Medicine, College of Health Sciences, Ebonyi State University Abakaliki, Abakaliki, Nigeria.ORCID https://orcid.org/0000-0002-4098-4898

Funding

World Health Organization 001
6 · The paper itself

Abstract

In January 2020, WHO released a rapid communication on use of molecular assays as initial tests for diagnosis of tuberculosis, recommending Truenat as a replacement for smear microscopy in TB diagnosis. This study was designed to assess perceived ease of use of Truenat among Laboratory staff as a new diagnostic tool for TB in Nigeria. This study used a cross-sectional design. All trained Laboratory personnel operating the Truenat Duo equipment in 38 Truenat sites in the country were included. Information was obtained using a pre-tested self-administered questionnaire. Ease of use of Truenat was assessed using twenty-three variables on a five-point Likert scale of 1-5. The variables were analyzed quantitatively and qualitatively. Good Ease of use of Truenat was determined by proportion of respondents who answered ≥70% of the variables in the positive. All 50 Truenat Laboratory staff participated in the study. (Response rate 100%). Majority, (58%) were male. The median estimated number of tests before Laboratory staff became proficient with Truenat machine was 9 (IQR, 4-20), median number of tests to be analyzed within eight working hours was 10, (IQR = 8-15) and median time to conduct a Truelab MTBPlus test from start to finish was 60 minutes (IQR = 60-80). The commonest operational challenge that required Molbio service support was Trueprep errors/blockage, 47.4%. Overall, mean ease of use score was 4.0±0.4. Majority, (76%) had Good Ease of use of Truenat. No factor significantly influenced Ease of use of Truenat. Truenat machine is easy to use for a trained laboratory staff with minimal technical support and hence could be rolled out easily and successfully by various National TB Programs. Considering the high Trueprep challenges reported, there is need for further studies into the common errors/challenges, the contexts surrounding them and the programmatic intervention to address the high rate of Trueprep equipment faults.

Identifiers

PMID39302944
PMCPMC11414918

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.