Evidence map›Paper›PMID 39302915›Full record

ArticleJournal of biomaterials applications2025

Boric acid and zinc borate doped graphene hydrogels designed for burn treatment: In vitro viability-biocompatibility tests and microbiological analysis.

Yasin Bayir, Beyzagül Erkayman, Abdulmecit Albayrak, Şaziye Sezin Palabiyik-Yücelik, Sümeyra Can, Hayrunisa Hanci, Fatih Tunç, Hamza Halici, Maide Sena Civelek, Melike Sevim and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biomaterials applications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yasin BayirDepartment of Biochemistry, Faculty of Pharmacy, Ataturk University, Erzurum, Türkiye.ORCID 0000-0003-3562-6727
Beyzagül ErkaymanDepartment of Pharmacology, Faculty of Pharmacy, Ataturk University, Erzurum, Türkiye.
Abdulmecit AlbayrakDepartment of Pharmacology, Faculty of Medicine, Ataturk University, Erzurum, Türkiye.
Şaziye Sezin Palabiyik-YücelikDepartment of Pharmaceutical Toxicology, Faculty of Pharmacy, Ataturk University, Erzurum, Türkiye.
Sümeyra CanDepartment of Chemistry, Faculty of Science, Ataturk University, Erzurum, Türkiye.
Hayrunisa HanciDepartment of Microbiology, Faculty of Pharmacy, Ataturk University, Erzurum, Türkiye.
Fatih TunçDepartment of Biochemistry, Faculty of Pharmacy, Ataturk University, Erzurum, Türkiye.
Hamza HaliciDepartment of Pharmacology, Faculty of Medicine, Ataturk University, Erzurum, Türkiye.
Maide Sena CivelekDepartment of Pharmacology, Faculty of Medicine, Ataturk University, Erzurum, Türkiye.
Melike SevimDepartment of Chemistry, Faculty of Science, Ataturk University, Erzurum, Türkiye.
Emir Enis YurdgülüDepartment of Biochemistry, Faculty of Pharmacy, Ataturk University, Erzurum, Türkiye.ORCID 0000-0002-9636-1753
Önder MetinDepartment of Chemistry, College of Sciences, Koc University, İstanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Boron, an essential element for human, can be a key factor in wound healing. For this reason, in this study, role of boron products (boric acid and zinc borate) and boron product doped new synthesized graphene hydrogels was investigated for burn healing via in vitro viability-biocompatibility tests and microbiological analysis. It has been determined that boric acid and zinc borate are effective against microbial agents that are frequently seen in burns. In L929 mouse fibroblast cell line, BA, ZB and graphene hydrogels did not show any toxic effects, either alone or doped Graphene Hydrogel forms, except at very high doses. These substances showed antioxidant properties by protecting cells against H

Indexed as

Biocompatible MaterialsBoratesBoric AcidsCell SurvivalGraphiteHydrogelsMaterials TestingAnimalsAnti-Bacterial AgentsAntioxidantsBurnsCell LineFibroblastsHydrogen PeroxideMiceWound HealingAnti-Bacterial AgentsAntioxidantsBiocompatible MaterialsBoratesboric acidBoric AcidsGraphiteHydrogelsHydrogen PeroxideZinczinc borateZinc CompoundsbiocompatibilityBoric acidgraphene hydrogelsmicrobiological analysisviabilityzinc borate

Identifiers

PMID39302915
PMCPMC11707965

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.