Evidence map›Paper›PMID 39302105›Full record

ArticleCancer research communications2024

Small-Molecule CCR4 Antagonists in Cutaneous T-cell Lymphoma.

José S Enriquez, Xiaohong Wang, Loka Reddy Velatooru, Wei Han, Pedram Bijani, Xiao Ni

Abstract read
In one paragraph

Article in Cancer research communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

José S EnriquezDepartment of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-9119-8176
Xiaohong WangDepartment of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-2700-092X
Loka Reddy VelatooruDepartment of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0003-1451-6879
Wei HanDepartment of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0009-0000-0744-5668
Pedram BijaniDepartment of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0001-8439-3179
Xiao NiDepartment of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-0154-446X

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

significanceOur findings are of interest to readers because they bring new evidence that small-molecule CCR4 antagonists may be an alternative therapeutic strategy to target CCR4+ CTCL cells. They may inhibit CCR4 function but not eradicate cells, so the side effects may be avoided or minimized.

Indexed as

Lymphoma, T-Cell, CutaneousReceptors, CCR4Antineoplastic AgentsHumansSkin NeoplasmsAntineoplastic AgentsCCR4 protein, humanReceptors, CCR4

Identifiers

PMID39302105
PMCPMC11494885

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.