Evidence map›Paper›PMID 39301895›Full record

Observational studyTherapeutic advances in respiratory disease

A multicenter observational study assessing the safety, feasibility, and complications of Bonastent in central airway obstruction.

Nagendra Y Madisi, Sana Ali, Daniel Greenberg, Gowthami Kobbari, Muhammad Salick, Anoosh Parimi, Ziad Boujaoude, Wissam Abouzgheib

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nagendra Y MadisiDepartment of Medicine, Pulmonary & Critical Care Medicine, Albany Medical Center, 16 New Scotland Avenue, Albany, NY 12208, USA.
Sana AliDepartment of Medicine, Pulmonary & Critical Care Medicine, Albany Medical Center, Albany, NY, USA.ORCID 0009-0000-0270-689X
Daniel GreenbergDepartment of Medicine, Pulmonary & Critical Care Medicine, Albany Medical Center, Albany, NY, USA.
Gowthami KobbariDepartment of Medicine, Pulmonary & Critical Care Medicine, Albany Medical Center, Albany, NY, USA.
Muhammad SalickDepartment of Medicine, Pulmonary & Critical Care Medicine, Albany Medical Center, Albany, NY, USA.
Anoosh ParimiDepartment of Medicine, Internal Medicine, Albany Medical Center, Albany, NY, USA.
Ziad BoujaoudeDepartment of Medicine, Interventional Pulmonology, Cooper University Hospital, Camden, NJ, USA.
Wissam AbouzgheibDepartment of Medicine, Interventional Pulmonology, Cooper University Hospital, Camden, NJ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelf-expandable metallic stents (SEMS) are increasingly used in the management of both malignant and nonmalignant airway stenosis. There are multiple stents available in the market; however, the current literature on the efficacy and safety of newly available 3rd generation SEMS (Bonastent) is extremely limited and only has data from single center studies.

objectivesTo report the efficacy and early (<7 days) and late (⩾7 days) complications in patients with central airway obstruction (CAO) treated with Bonastent placement at two institutions.

designWe performed a retrospective analysis of data of consecutive patients who underwent therapeutic bronchoscopy and Bonastent placement at two tertiary care university hospitals between January 2019 and November 2023.

methodsBonastent deployment was performed in the operating room. Stents were deployed using rigid or flexible bronchoscopy under direct visualization with a flexible bronchoscope and in conjunction with fluoroscopic guidance. We then analyzed the effectiveness, short-term, and long-term complications of Bonastent placement.

resultsA total of 107 Bonastents® were placed in 96 patients. The most common etiology of CAO was malignancy, 92.7% (

conclusionOur study is the first multicenter study that found a good safety profile with a low complication rate after tracheobronchial Bonastent placement with improvement in symptoms soon after stent placement.

Indexed as

Airway ObstructionBronchoscopyFeasibility StudiesSelf Expandable Metallic StentsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedProsthesis DesignRetrospective StudiesTime FactorsTracheal StenosisTreatment Outcomeairway obstructionBonastentendobronchial stent

Identifiers

PMID39301895
PMCPMC11437588

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.