ArticleMagnetic resonance in medicine2025
Calibration-free whole-brain CEST imaging at 7T with parallel transmit pulse design for saturation homogeneity utilizing universal pulses (PUSHUP).
Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Multi-Contrast Human Brain CEST MRI at 11.7 T: First In Vivo Demonstration.Magnetic resonance in medicine · 2026Article
- 10.5 T In Vivo Head Imaging With Universal RF Shimming.Magnetic resonance in medicine · 2026Article
- Generalization of Optimal Control Saturation Pulse Design for Robust and High CEST Contrast.Magnetic resonance in medicine · 2026Article
- Ready for Routine: Homogeneous, High-Resolution, and Multicontrast Whole-Brain MRI at 7 Tesla in Short Scan Time With "plug-and-Play" pTx Sequences.Investigative radiology · 2025Article
- Rapid and simplified post-processing for simultaneousMagnetic resonance in medicine · 2025Article
- MPRAGEMagnetic resonance in medicine · 2025Article
- Calibration-free whole-brain CEST imaging at 7T with parallel transmit pulse design for saturation homogeneity utilizing universal pulses (PUSHUP).Magnetic resonance in medicine · 2025Article
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Authors and funding
9 authors.
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Abstract
purposeChemical exchange saturation transfer (CEST) measurements at ultra-high field (UHF) suffer from strong saturation inhomogeneity. Retrospective correction of this inhomogeneity is possible to some extent, but requires a time-consuming repetition of the measurement. Here, we propose a calibration-free parallel transmit (pTx)-based saturation scheme that homogenizes the saturation over the imaging volume, which we call PUlse design for Saturation Homogeneity utilizing Universal Pulses (PUSHUP). THEORY: Magnetization transfer effects depend on the saturation
methodsPUSHUP was combined with a whole-brain three-dimensional-echo planar imaging (3D-EPI) readout. Two PUSHUP saturation modules were calculated by either applying whole-brain or cerebellum masks to the database maps. The saturation homogeneity and the group mean CEST amplitudes were calculated for different
resultsIn contrast to CP saturation, where accurate CEST maps were impossible to obtain in the cerebellum, even with extensive
conclusionThe presented method allows for homogeneous whole-brain CEST imaging at 7 Tesla without the need of a repetition-based
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