Evidence map›Paper›PMID 39301152›Full record

ArticleCurrent physical medicine and rehabilitation reports2023

Dysphagia in Parkinson Disease: Part II-Current Treatment Options and Insights from Animal Research.

Maryann N Krasko, Denis Michael Rudisch, Ryan J Burdick, Nicole E Schaen-Heacock, Courtney K Broadfoot, Alex F Nisbet, Nicole Rogus-Pulia, Michelle R Ciucci

Abstract read
In one paragraph

Article in Current physical medicine and rehabilitation reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Positron Emission Tomography (PET) Neuroimaging of theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. Positron emission tomography neuroimaging of [Frontiers in neuroscience · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maryann N KraskoDepartment of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin-Madison, 1300 University Ave, Madison, WI 53706, USA.ORCID 0000-0001-5982-6729
Denis Michael RudischDepartment of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin-Madison, 1300 University Ave, Madison, WI 53706, USA.ORCID 0000-0002-2201-6420
Ryan J BurdickDepartment of Medicine, Division of Geriatrics and Gerontology, School of Medicine and Public Health, University of Wisconsin-Madison, 1685 Highland Avenue, Madison, WI 53705, USA.ORCID 0000-0003-0424-0207
Nicole E Schaen-HeacockDepartment of Medicine, Division of Geriatrics and Gerontology, School of Medicine and Public Health, University of Wisconsin-Madison, 1685 Highland Avenue, Madison, WI 53705, USA.ORCID 0000-0002-8053-7953
Courtney K BroadfootDepartment of Medicine, Division of Geriatrics and Gerontology, School of Medicine and Public Health, University of Wisconsin-Madison, 1685 Highland Avenue, Madison, WI 53705, USA.ORCID 0000-0002-0355-4434
Alex F NisbetPerelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA 19104, USA.ORCID 0000-0002-4083-7230
Nicole Rogus-PuliaDepartment of Medicine, Division of Geriatrics and Gerontology, School of Medicine and Public Health, University of Wisconsin-Madison, 1685 Highland Avenue, Madison, WI 53705, USA.ORCID 0000-0001-7294-4180
Michelle R CiucciDepartment of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin-Madison, 1300 University Ave, Madison, WI 53706, USA.ORCID 0000-0002-9913-8784

Funding

University of Wisconsin Voice Research Training Program (T32)T32DC009401 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI Susan Lynn Thibeault · 2009 to 2026
$6.3M
Preclinical trial for dysarthria treatment in Parkinson diseaseR01DC018584 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI CIUCCI, MICHELLE RENEE · 2021 to 2025
$3.3M
Influence of neuromuscular pathology on parkinsonian communication deficitsR01DC014358 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI CIUCCI, MICHELLE RENEE, CONNOR, NADINE P · 2015 to 2019
$2.7M
Impact of Novel Rehabilitative Approaches FOR Dysphagia in Patients with Alzheimer's Disease and Related DementiasK76AG068590 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI ROGUS-PULIA, NICOLE M · 2020 to 2023
$1.3M
Vocal dysfunction and vagally mediated brainstem pathology in prodromal Parkinson diseaseF31DC022161 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI KRASKO, MARYANN N · 2024 to 2024
$43k
NIA NIH HHS K76 AG068590NIDCD NIH HHS F31 DC022161NIDCD NIH HHS R01 DC014358NIDCD NIH HHS R01 DC018584NIDCD NIH HHS T32 DC009401
6 · The paper itself

Abstract

Purpose of Review: Dysphagia is highly prevalent in Parkinson disease (PD) but is not typically identified nor treated until later in the disease process. This review summarizes current pharmacological, surgical, and behavioral treatments for PD-associated dysphagia and contributions from translational animal research. Recent Findings: Swallowing is a complex physiologic process controlled by multiple brain regions and neurotransmitter systems. As such, interventions that target nigrostriatal dopamine dysfunction have limited or detrimental effects on swallowing outcomes. Behavioral interventions can help target PD-associated dysphagia in Summary: Dysphagia is an early, common, and debilitating sign of PD. Current pharmacological and surgical interventions are not effective in ameliorating swallowing dysfunction; behavioral intervention remains the most effective approach for dysphagia treatment. Animal research has advanced our understanding of mechanisms underlying PD and PD-associated dysphagia, and continues to show translational promise for the study of dysphagia treatment options.

Indexed as

Animal modelsDysphagiaParkinson diseasePathophysiologySwallowingTreatment

Identifiers

PMID39301152
PMCPMC11411792

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.