Evidence map›Paper›PMID 39300908›Full record

ReviewACS synthetic biology2024

Ten Years of the Synthetic Biology Summer Course at Cold Spring Harbor Laboratory.

Karmella A Haynes, Lauren B Andrews, Chase L Beisel, James Chappell, Christian E Cuba Samaniego, John E Dueber, Mary J Dunlop, Elisa Franco, Julius B Lucks, Vincent Noireaux and 4 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in ACS synthetic biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Karmella A HaynesWallace H. Coulter Department of Biomedical Engineering, Emory University, Atlanta, Georgia 30345, United States.ORCID 0000-0002-5975-577X
Lauren B AndrewsDepartment of Chemical Engineering, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States.ORCID 0000-0003-1627-1430
Chase L BeiselHelmholtz Institute for RNA-Based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), 97080 Würzburg, Germany.
James ChappellBiosciences Department, Rice University, Houston, Texas 77005, United States.ORCID 0000-0001-7367-1524
Christian E Cuba SamaniegoDepartment of Computational Biology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, United States.
John E DueberDepartment of Bioengineering, University of California Berkeley, Berkeley, California 94720, United States.ORCID 0000-0001-8404-7153
Mary J DunlopBiomedical Engineering, Boston University, Boston, Massachusetts 02215, United States.ORCID 0000-0002-9261-8216
Elisa FrancoMechanical and Aerospace Engineering, Bioengineering, University of California, Los Angeles, California 90095, United States.ORCID 0000-0003-1103-2668
Julius B LucksDepartment of Chemical and Biological Engineering and Center for Synthetic Biology, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-0619-6505
Vincent NoireauxSchool of Physics and Astronomy, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0002-5213-273X
David F SavageDepartment of Molecular and Cell Biology, University of California Berkeley, Berkeley, California 94720, United States.
Pamela A SilverDepartment of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, United States.ORCID 0000-0002-7856-4071
Michael SmanskiDepartment of Biochemistry, Molecular Biology, and Biophysics and Biotechnology Institute, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0002-6029-8326
Eric YoungChemical Engineering, Worcester Polytechnic Institute, Worcester, Massachusetts 01609, United States.ORCID 0000-0001-5276-2873

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Cold Spring Harbor Laboratory (CSHL) Summer Course on Synthetic Biology, established in 2013, has emerged as a premier platform for immersive education and research in this dynamic field. Rooted in CSHL's rich legacy of biological discovery, the course offers a comprehensive exploration of synthetic biology's fundamentals and applications. Led by a consortium of faculty from diverse institutions, the course structure seamlessly integrates practical laboratory sessions, exploratory research rotations, and enriching seminars by leaders in the field. Over the years, the curriculum has evolved to cover essential topics such as cell-free transcription-translation, DNA construction, computational modeling of gene circuits, engineered gene regulation, and CRISPR technologies. In this review, we describe the history, development, and structure of the course, and discuss how elements of the course might inform the development of other short courses in synthetic biology. We also demonstrate the course's impact beyond the lab with a summary of alumni contributions to research, education, and entrepreneurship. Through these efforts, the CSHL Summer Course on Synthetic Biology remains at the forefront of shaping the next generation of synthetic biologists.

Indexed as

Synthetic BiologyCurriculumGene Regulatory NetworksHumansLaboratoriescomputational modelingCRISPRDNA constructioneducationgene regulationTXTL

Identifiers

PMID39300908
PMCPMC11421210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.