Evidence map›Paper›PMID 39300573›Full record

ArticleInjury epidemiology2024

Therapeutic errors involving diabetes medications reported to United States poison centers.

Ashley Thurgood Giarman, Hannah L Hays, Jaahnavi Badeti, Natalie I Rine, Henry A Spiller, Motao Zhu, Gary A Smith

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In one paragraph

Article in Injury epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ashley Thurgood GiarmanCenter for Injury Research and Policy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
Hannah L HaysCenter for Injury Research and Policy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
Jaahnavi BadetiCenter for Injury Research and Policy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
Natalie I RineCentral Ohio Poison Center, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
Henry A SpillerCentral Ohio Poison Center, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
Motao ZhuCenter for Injury Research and Policy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
Gary A SmithCenter for Injury Research and Policy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA. gary.smith@nationwidechildrens.org.

Funding

Child Injury Prevention Alliance No Grant Number
6 · The paper itself

Abstract

backgroundTo investigate the characteristics and trends of therapeutic errors that occur outside of healthcare facilities involving diabetes medications reported to US poison centers.

methodsNational Poison Data System data from 2000 to 2021 were retrospectively analyzed.

resultsThere were 157,623 exposure cases of non-healthcare facility-related therapeutic errors associated with diabetes medications as the primary substance reported to US poison centers from 2000 to 2021. The rate of all therapeutic errors involving diabetes medications increased by 279.8% from 2000 to 2011, followed by a slower 15.0% increase to 2021. Half (50.1%) of the exposure cases were treated/evaluated and released and 44.1% did not receive treatment in a healthcare facility; however, 9.9% experienced a serious medical outcome, including 17 fatalities, and 1.0% were admitted to a critical care unit and 2.2% to a non-critical care unit. Insulin had the highest rates of therapeutic errors and serious medical outcomes, while sulfonylureas and insulin had the highest medical hospital admission rates. Metformin accounted for 59% (n = 10) of fatalities.

conclusionsAlthough most cases of therapeutic errors involving diabetes medications had no or minimal clinical consequences, an important minority were associated with a serious medical outcome or medical hospital admission. Increased efforts to prevent therapeutic errors involving diabetes medications are warranted.

Indexed as

Adverse eventDiabetesNational Poison Data SystemTherapeutic error

Identifiers

PMID39300573
PMCPMC11412010

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.