ArticleDiagnostic pathology2024
Oral mucosal changes caused by nicotine pouches: case series.
Article in Diagnostic pathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Acute cell‑death and lysosomal stress responses to nicotine and cigarette smoke extract in human mesenchymal stromal cells.Archives of toxicology · 2026Article
- Chili Pepper Flavourants in "Heat" and "Unflavoured" Oral Nicotine Pouches Marketed in the United States.bioRxiv : the preprint server for biology · 2026Article
- Oral Nicotine Pouch Use and Associations with Periodontal Status and Salivary Microbiome Dysbiosis.JDR clinical and translational research · 2026Article
- Awareness and use of nicotine pouches among adults in the Kingdom of Saudi Arabia.Scientific reports · 2026Article
- Nicotine pouches: an aid in smoking cessation, or a new public health hazard?Internal and emergency medicine · 2026Review
- Clinical and histopathological manifestations of snus use in Germany: parallels to betel nut-related oral submucous fibrosis in Asia.Virchows Archiv : an international journal of pathology · 2026Article
- Instagram Memes of Oral Nicotine Pouches: Content Analysis Study.Online journal of public health informatics · 2026Article
- Patterns of tobacco product use among US adults who use nicotine pouches and the association between nicotine pouch use and tobacco product use cessation.Tobacco control · 2026Article
- Activated carbon attenuates nicotine and Candida albicans-induced oral leukoplakia via modulation of IL-17R signaling and oxidative stress: an in vivo study.Head & face medicine · 2026Article
- The association between duration of nicotine pouch use and oral mucosal lesions in male dental students and interns: A cross-sectional study.Tobacco induced diseases · 2026Article
- Nicotine pouches, oral cancer and tobacco harm reduction: current evidence and research priorities.Frontiers in oral health · 2026Review
- Correction: Oral mucosal changes caused by nicotine pouches: case series.Diagnostic pathology · 2025Article
- Comparative evaluation of artificial saliva and complete artificial saliva as solvent vehicles forFrontiers in toxicology · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral nicotine pouches are the latest products in the tobacco industry. They are manufactured by large tobacco companies and entice tobacco or nicotine addicts, although the products are presented as a 'harmless choice.' Nevertheless, dentists and oral health specialists worry about oral mucosal changes due to product interactions with the oral mucosa. Unfortunately, there are no case reports of oral mucosal changes from nicotine pouches that are also investigated histopathologically. The aim of the present study was to visually and histopathologically investigate oral mucosal changes in nicotine pouch users. An online retrospective survey regarding medical and dental health, dietary habits, and tobacco consumption habits was conducted (n = 50). Respondents were selected for further intraoral and histopathological investigation based on the inclusion criteria. All five respondents had oral lesions that were histopathologically analyzed. Visually, the lesions varied in form and intensity, but all appeared white at the location where the pouches were placed. Histopathological analyses revealed parakeratosis with acanthotic epithelium, intraepithelial and connective tissue oedema, and chronic inflammatory infiltration with lymphocytes and macrophages. Participants received information about nicotine cessation and oral health recommendations. In conclusion, nicotine pouches significantly impacted oral mucosa with white lesions that revealed important changes at the cellular level.
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