Evidence map›Paper›PMID 39300443›Full record

Trial reportBMC medicine2024

A guided single session intervention to reduce intrusive memories of work-related trauma: a randomised controlled trial with healthcare workers in the COVID-19 pandemic.

Marie Kanstrup, Laura Singh, Elisabeth Johanna Leehr, Katarina E Göransson, Sara Ahmed Pihlgren, Lalitha Iyadurai, Oili Dahl, Ann-Charlotte Falk, Veronica Lindström, Nermin Hadziosmanovic and 3 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04460014 (Reducing Intrusive Memories After Trauma Via a Simple Cognitive Intervention During COVID-19 in Hospital Staff), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04460014 nacompletednot on this map

Reducing Intrusive Memories After Trauma Via a Simple Cognitive Intervention During COVID-19 in Hospital Staff: "EKUT-P" (Enkel Kognitiv Uppgift Efter Trauma Under COVID-19 - sjukvårdspersonal) - A Randomized Controlled Trial (RCT)

TypeinterventionalSponsorKarolinska InstitutetRan2020 to 2022Enrolled164ConditionsIntrusive Memories of Traumatic Event(s), Post Traumatic Stress DisorderArmsSimple cognitive task intervention, Attention Placebo
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marie Kanstrup *Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Laura Singh *Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Elisabeth Johanna Leehr *Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Katarina E GöranssonEmergency and Reparative Medicine Theme, Karolinska University Hospital, Stockholm, Sweden.
Sara Ahmed PihlgrenDivision of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Lalitha IyaduraiP1vital Products Ltd, Wallingford, Oxfordshire, UK.
Oili DahlDivision of Nursing, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
Ann-Charlotte FalkDepartment for Health Promoting Science, Sophiahemmet University, Stockholm, Sweden.
Veronica LindströmDepartment for Health Promoting Science, Sophiahemmet University, Stockholm, Sweden.
Nermin HadziosmanovicUppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
Katja GabryschUppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
Michelle L MouldsSchool of Psychology, The University of New South Wales, UNSW Sydney, Sydney, Australia.
Emily A HolmesDivision of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. emily.holmes@uu.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntrusive memories of psychologically traumatic events bring distress both sub-clinically and clinically. This parallel-group, two-arm randomised controlled trial evaluated the effect of a brief behavioural intervention on reducing intrusive memories in frontline healthcare workers exposed to traumatic events during the COVID-19 pandemic.

methodsParticipants with at least two intrusive memories of work-related trauma in the week before recruitment were randomised 1:1 to an imagery-competing task intervention (n = 73) or attention-based control task (n = 71). The number of intrusive memories was assessed at baseline and 5 weeks after the guided session (primary endpoint).

resultsThe intervention significantly reduced intrusive memory frequency compared with control [intervention Mdn = 1.0 (IQR = 0-3), control Mdn = 5.0 (IQR = 1-17); p < 0.0001, IRR = 0.30; 95% CI = 0.17-0.53] and led to fewer post-traumatic stress-related symptoms at 1, 3 and 6 month follow-ups (secondary endpoints). Participants and statisticians were blinded to allocation. Adverse events data were acquired throughout the trial, demonstrating safety. There was high adherence and low attrition.

conclusionsThis brief, single-symptom, repeatable digital intervention for subclinical-to-clinical samples after trauma allows scalability, taking a preventing-to-treating approach after trauma.

trial registration2020-07-06, ClinicalTrials.gov identifier: NCT04460014.

Indexed as

COVID-19Health PersonnelStress Disorders, Post-TraumaticAdultFemaleHumansImagery, PsychotherapyMaleMiddle AgedPandemicsSARS-CoV-2Digital interventionHealthcare workersIntrusive memoryMental healthPandemicPost-traumatic stress disorderPrevention-to-treatingPsychological trauma

Identifiers

PMID39300443
PMCPMC11414261

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.