Evidence map›Paper›PMID 39300419›Full record

ArticleBMC public health2024

Personalized sleep and nutritional strategies to combat adverse effects of night shift work: a controlled intervention protocol.

Maaike van der Rhee, Johanneke E Oosterman, Suzan Wopereis, Gijsbertus T J van der Horst, Inês Chaves, Martijn E T Dollé, Alex Burdorf, Linda W M van Kerkhof, Heidi M Lammers-Van der Holst

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06147089 (Biomarker Based Intervention Strategies to Combat Adverse Effects of Shift Work), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06147089 nacompletednot on this map

Biomarker Based Intervention Strategies to Combat Adverse Effects of Shift Work

TypeinterventionalSponsorErasmus Medical CenterRan2023 to 2025Enrolled57ConditionsShift-Work Related Sleep DisturbanceArmsSleep Intervention, Nutritional intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maaike van der RheeDepartment of Public Health, Erasmus MC, Rotterdam, 3000 CA, The Netherlands. m.vanderrhee@erasmusmc.nl.
Johanneke E OostermanResearch Group Microbiology & Systems Biology, TNO, Organization for Applied Scientific Research, Leiden, 2333 BE, The Netherlands.
Suzan WopereisResearch Group Microbiology & Systems Biology, TNO, Organization for Applied Scientific Research, Leiden, 2333 BE, The Netherlands.
Gijsbertus T J van der HorstDepartment Molecular Genetics, Erasmus MC, Rotterdam, 3000 CA, The Netherlands.
Inês ChavesDepartment Molecular Genetics, Erasmus MC, Rotterdam, 3000 CA, The Netherlands.
Martijn E T DolléCentre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, 3721 MA, The Netherlands.
Alex BurdorfDepartment of Public Health, Erasmus MC, Rotterdam, 3000 CA, The Netherlands.
Linda W M van KerkhofCentre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, 3721 MA, The Netherlands.
Heidi M Lammers-Van der HolstDepartment of Public Health, Erasmus MC, Rotterdam, 3000 CA, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWorking during the night interferes with the timing of normal daily activities and is associated with an increased risk of chronic diseases. Under controlled experimental conditions, interventions focusing on sleep and nutrition can mitigate the short-term adverse effects of shift work. However, it is unclear how these results translate to real-life, how they can be targeted to individual conditions, and how they relate to long-term health. Therefore, the current study aims to implement a personalized sleep and nutritional intervention among night shift workers in the field.

methodsA non-blinded controlled intervention study is used, consisting of a run-in period, an intervention of 3 months, post-intervention measurements, and a follow-up after 12 months. Three study arms are included: sleep intervention, nutritional intervention, and control group (n = 25 each). Participants are healthy 18-60-year male night shift workers, with at least one year of experience in night shift work. Information from the run-in period will be used to personalize the interventions. The main outcomes are sleep measurements and continuous interstitial glucose levels. Furthermore, general health biomarkers and parameters will be determined to further evaluate effects on long-term health. DISCUSSION: This study aims to mitigate negative health consequences associated with night shift work by introducing two personalized preventive interventions. If proven effective, the personalized interventions may serve as practical solutions that can have a meaningful impact on the sustainable health and employability of night shift workers. This study will thereby contribute to the current need for high-quality data on preventative strategies for night shift work in a real-life context.

trial registrationThis trial has been registered under ClinicalTrials.gov Identifier NCT06147089. Registered 27 November 2023.

Indexed as

Shift Work ScheduleSleepAdolescentAdultHumansMaleMiddle AgedSleep Disorders, Circadian RhythmWork Schedule ToleranceYoung AdultCircadian disruptionGlucose homeostasisMetabolic healthNight shiftOccupational healthPrecision nutritionReal-life interventionShift workSleep

Identifiers

PMID39300419
PMCPMC11414285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.