Evidence map›Paper›PMID 39300387›Full record

ArticleBMC nephrology2024

Effect of central dialysis fluid delivery system on markers of inflammation in hemodialysis patients.

Yanhong Ni, Wenhui Wu, Hua Zhou, Min Li, Xiying Zhu, Hongyan Niu, Jinfeng Liu, Lina Xue, Yeqian Liu, Min Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yanhong Ni *Department of Nephrology, The Third Affiliated Hospital of Soochow University, Jiangsu Province, No. 185 Juqian Road, Changzhou, 213003, China.
Wenhui Wu *Department of Nephrology, The Third Affiliated Hospital of Soochow University, Jiangsu Province, No. 185 Juqian Road, Changzhou, 213003, China.
Hua ZhouDepartment of Nephrology, The Third Affiliated Hospital of Soochow University, Jiangsu Province, No. 185 Juqian Road, Changzhou, 213003, China.
Min LiDepartment of Nephrology, The Third Affiliated Hospital of Soochow University, Jiangsu Province, No. 185 Juqian Road, Changzhou, 213003, China.
Xiying ZhuDepartment of Nephrology, The Third Affiliated Hospital of Soochow University, Jiangsu Province, No. 185 Juqian Road, Changzhou, 213003, China.
Hongyan NiuDepartment of Nephrology, The Third Affiliated Hospital of Soochow University, Jiangsu Province, No. 185 Juqian Road, Changzhou, 213003, China.
Jinfeng LiuDepartment of Nephrology, The Third Affiliated Hospital of Soochow University, Jiangsu Province, No. 185 Juqian Road, Changzhou, 213003, China.
Lina XueDepartment of Nephrology, The Third Affiliated Hospital of Soochow University, Jiangsu Province, No. 185 Juqian Road, Changzhou, 213003, China.
Yeqian LiuDepartment of Nephrology, The Third Affiliated Hospital of Soochow University, Jiangsu Province, No. 185 Juqian Road, Changzhou, 213003, China.
Min YangDepartment of Nephrology, The Third Affiliated Hospital of Soochow University, Jiangsu Province, No. 185 Juqian Road, Changzhou, 213003, China. sunshineyangm@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe utilization of ultrapure dialysate has been shown to decrease dialysate contamination and mitigate inflammatory responses. The central dialysate delivery system (CDDS) has the potential to attain a level of purity similar to ultrapure dialysate. Nevertheless, there is limited research examining the impact of CDDS on inflammation in comparison to single-patient dialysis fluid delivery system(SPDDS). This study aims to investigate the effects of CDDS utilizing ultrapure dialysate on ameliorating the microinflammatory state in hemodialysis patients.

methodA retrospective cohort clinical study enrolled a total of 125 hemodialysis patients, with 58 patients from the CDDS unit and 67 patients from the SPDDS unit. Each participant was monitored for a period of 6 months, and the repeated measurement data was analyzed using a generalized linear mixed models (GLMM).

resultsThe average age of the studty cohort was 56.22 ± 12.64 years. The GLMM analysis showed a significant time*group interaction effect on hs-CRP changes over the follow-up period (β = -1.966, F

conclusionUsing ultrapure dialysate in the CDDS is associated with an improvement in hs-CRP levels compared to standard dialysate, which might confer long-term clinical advantages.

Indexed as

BiomarkersInflammationRenal DialysisAdultAgedbeta 2-MicroglobulinCohort StudiesC-Reactive ProteinDialysis SolutionsFemaleHemodialysis SolutionsHumansKidney Failure, ChronicMaleMiddle AgedRetrospective Studiesbeta 2-MicroglobulinBiomarkersC-Reactive ProteinDialysis SolutionsHemodialysis SolutionsCDDSCentral Dialysate Delivery systemInflammationMaintenance hemodialysisUltrapure dialysate

Identifiers

PMID39300387
PMCPMC11414299

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.