Evidence map›Paper›PMID 39300232›Full record

ArticleScientific reports2024

A mathematical insight to control the disease psoriasis using mesenchymal stem cell transplantation with a biologic inhibitor.

Subhankar Kushary, Xianbing Cao, Tushar Ghosh, Priti Kumar Roy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Subhankar KusharyDepartment of Mathematics, Jadavpur University, Kolkata, West Bengal, 700032, India.
Xianbing CaoSchool of Mathematics and Statistics, Beijing Technology and Business University, Beijing, 100048, China.
Tushar GhoshDepartment of Mathematics, Jadavpur University, Kolkata, West Bengal, 700032, India.
Priti Kumar RoyDepartment of Mathematics, Jadavpur University, Kolkata, West Bengal, 700032, India. pritiju@gmail.com.

Funding

Project of National Statistical Science Foundation of China 2021LD01
6 · The paper itself

Abstract

Psoriasis is a chronic, non-contagious, immune-mediated skin disorder. Inflammation of the skin's surface is characterised by scaly white, red, or silvery spots that occur due to the hyper-proliferation of keratinocytes in the epidermal layer. Primarily, pharmaceutical drugs or immune therapy are used to treat psoriasis. We are all aware that, certain therapeutic strategies can have some adverse effects, and over time, that hidden inflammation may manifest. This article introduces a mathematical model for psoriasis, formulated by employing a set of nonlinear ordinary differential equations (ODEs) that describe the densities of T-cells, dendritic cells (DCs), keratinocytes, and mesenchymal stromal cells (MSCs) as basic cell populations. A tumor necrosis factor-

Indexed as

Mesenchymal Stem Cell TransplantationPsoriasisDendritic CellsHumansKeratinocytesMesenchymal Stem CellsModels, TheoreticalT-LymphocytesTumor Necrosis Factor-alphaTumor Necrosis Factor-alphaMesenchymal stromal cellsOptimal controlPulsed manner

Identifiers

PMID39300232
PMCPMC11413237

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.