Evidence map›Paper›PMID 39300207›Full record

ArticleScientific reports2024

Expression patterns of housekeeping genes and tissue-specific genes in black goats across multiple tissues.

Chaobin Qin, Dong Wang, Hongbing Han, Yanhong Cao, Xiaobo Wang, Zeyi Xuan, Mingsong Wei, Zhipeng Li, Qingyou Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Strawberry atlas:PeerJ · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chaobin Qin *School of Animal Science and Technology, Guangxi University, Nanning, 530004, China.
Dong Wang *School of Animal Science and Technology, Guangxi University, Nanning, 530004, China.
Hongbing HanBeijing Key Laboratory of Animal Genetic Improvement, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.
Yanhong CaoGuangxi Vocational University of Agriculture, Nanning, 530007, Guangxi, China.
Xiaobo WangHenan Academy of Crops Molecular Breeding/The Shennong Laboratory, Zhengzhou, 450099, Henan, China.
Zeyi XuanGuangxi Vocational University of Agriculture, Nanning, 530007, Guangxi, China.
Mingsong WeiGuangxi Vocational University of Agriculture, Nanning, 530007, Guangxi, China. 175159461@qq.com.
Zhipeng LiSchool of Animal Science and Technology, Guangxi University, Nanning, 530004, China. zp.li@gxu.edu.cn.
Qingyou LiuGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, 528225, China. qyliu-gene@gxu.edu.cn.

Funding

National Key Research and Development Program of China 2021YFD1300901the Guangxi Science and Technology Program AB18294046the Research project collaboration with Guangxi Vocational University of Agriculture and Technology in 2023 XKJ2333
6 · The paper itself

Abstract

Black goats are a significant meat breed in southern China. To investigate the expression patterns and biological functions of genes in various tissues of black goats, we analyzed housekeeping genes (HKGs), tissue-specific genes (TSGs), and hub genes (HUBGs) across 23 tissues. Additionally, we analyzed HKGs in 13 tissues under different feeding conditions. We identified 2968 HKGs, including six important ones. Interestingly, HKGs in grazing black goats demonstrated higher and more stable expression levels. We discovered a total of 9912 TSGs, including 134 newly identified ones. The number of TSGs for mRNA and lncRNA were nearly equal, with 127 mRNA TSGs expressed solely in one tissue. Additionally, the predicted functions of tissue-specific long non-coding RNAs (lncRNAs) targeting mRNAs corresponded with the physiological functions of the tissues.Weighted gene co-expression network analysis (WGCNA) constructed 30 modules, where the dark grey module consists almost entirely of HKGs, and TSGs are located in modules most correlated with their respective tissues. Additionally, we identified 289 HUBGs, which are involved in regulating the physiological functions of their respective tissues. Overall, these identified HKGs, TSGs, and HUBGs provide a foundation for studying the molecular mechanisms affecting the genetic and biological processes of complex traits in black goats.

Indexed as

Genes, EssentialGoatsOrgan SpecificityAnimalsGene Expression ProfilingGene Expression RegulationGene Regulatory NetworksRNA, Long NoncodingRNA, MessengerRNA, Long NoncodingRNA, MessengerDifferent feeding methods for black goatsGene expressionHousekeeping genesHub genesTissue-specific genes

Identifiers

PMID39300207
PMCPMC11413040

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.