Evidence map›Paper›PMID 39298362›Full record

ArticleThe Journal of antimicrobial chemotherapy2024

Retrospective evaluation of rapid genotypic ID and phenotypic AST systems on positive blood culture turnaround time and simulated potential impacts on bloodstream infection management.

Ismail Yuceel-Timur, Elise Thierry, Delphine Chainier, Ibrahima Ndao, Maud Labrousse, Carole Grélaud, Yohann Bala, Olivier Barraud

Abstract read
In one paragraph

Article in The Journal of antimicrobial chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Diagnostic stewardship in sepsis: minding the gap from the microbiology lab to ward.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ismail Yuceel-TimurGlobal Medical Affairs, bioMérieux, Marcy L'Etoile, France.
Elise ThierryClinical Investigation Center CIC1435, Inserm, CHU Limoges, Limoges, France.
Delphine ChainierInserm, University of Limoges, CHU Limoges, Limoges UMR 1092, France.
Ibrahima NdaoClinical Investigation Center CIC1435, Inserm, CHU Limoges, Limoges, France.
Maud LabrousseClinical Investigation Center CIC1435, Inserm, CHU Limoges, Limoges, France.
Carole GrélaudInserm, University of Limoges, CHU Limoges, Limoges UMR 1092, France.
Yohann BalaGlobal Medical Affairs, bioMérieux, Marcy L'Etoile, France.ORCID 0009-0002-6265-8484
Olivier BarraudClinical Investigation Center CIC1435, Inserm, CHU Limoges, Limoges, France.ORCID 0000-0003-2015-9206

Funding

bioMérieux SA
6 · The paper itself

Abstract

backgroundBloodstream infections are linked to heightened morbidity and mortality rates. The consequences of delayed antibiotic treatment can be detrimental. Effective management of bacteraemia hinges on rapid antimicrobial susceptibility testing.

objectivesThis retrospective study examined the influence of the VITEK® REVEAL™ Rapid AST system on positive blood culture (PBC) management in a French tertiary hospital. MATERIALS AND

methodsBetween November 2021 and March 2022, 79 Gram-negative monomicrobial PBC cases underwent testing with both VITEK®REVEAL™ and VITEK®2 systems.

resultsThe study found that VITEK®REVEAL™ yielded better results than the standard of care, significantly shortening the time to result (7.0 h compared to 9.6 h) as well as the turnaround time (15 h compared to 31.1 h) when applied for all isolates.

conclusionsThis study implies that the use of VITEK®REVEAL™ enables swift adaptations of antibiotic treatment strategies. By considerably minimizing the turnaround time, healthcare professionals can promptly make necessary adjustments to therapeutic regimens. Notably, these findings underscore the potential of VITEK®REVEAL™ in expediting appropriate antibiotic interventions, even in less ideal conditions. Further studies in varied laboratory contexts are required to validate these encouraging outcomes.

Indexed as

Anti-Bacterial AgentsBacteremiaBlood CultureMicrobial Sensitivity TestsFranceGenotypeGram-Negative BacteriaHumansPhenotypeRetrospective StudiesTertiary Care CentersTime FactorsAnti-Bacterial Agents

Identifiers

PMID39298362
PMCPMC11412238

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.