Evidence map›Paper›PMID 39298112›Full record

ArticleAmerican journal of clinical dermatology2024

KECORT Study: An International e-Delphi Study on the Treatment of KEloids Using Intralesional CORTicosteroids in Clinical Practice.

Qi Yin, Albert Wolkerstorfer, Oren Lapid, Khatera Qayumi, Murad Alam, Firas Al-Niaimi, Ofir Artzi, Martijn B A van Doorn, Ioannis Goutos, Merete Haedersdal and 16 more

Abstract read
In one paragraph

Article in American journal of clinical dermatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Comprehensive Update on Keloid Management.Archives of plastic surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Qi YinDepartment of Dermatology, Amsterdam UMC location University of Amsterdam, Meibergdreef 9, 1100 DD, Amsterdam, The Netherlands. q.yin@amsterdamumc.nl.
Albert WolkerstorferDepartment of Dermatology, Amsterdam UMC location University of Amsterdam, Meibergdreef 9, 1100 DD, Amsterdam, The Netherlands.
Oren LapidDepartment of Plastic, Reconstructive and Hand Surgery, Amsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
Khatera QayumiDepartment of Dermatology, Amsterdam UMC location University of Amsterdam, Meibergdreef 9, 1100 DD, Amsterdam, The Netherlands.
Murad AlamDepartments of Dermatology, Otolaryngology, Surgery, and Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Firas Al-NiaimiTaktouk Clinic, London, UK.
Ofir ArtziDivision of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Martijn B A van DoornDepartment of Dermatology, Erasmus Medical Center, Rotterdam, The Netherlands.
Ioannis GoutosThe London Scar Clinic, 152 Harley Street, London, W1G 7LH, UK.
Merete HaedersdalDepartment of Dermatology, Copenhagen University Hospital, Bispebjerg, Copenhagen, Denmark.
Chao-Kai HsuDepartment of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Woraphong ManuskiattiDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Stan MonstreyDepartment of Plastic Surgery, Ghent University Hospital, Gent, Belgium.
Thomas A MustoeFeinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Rei OgawaDepartment of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, Tokyo, Japan.
David OzogDepartment of Dermatology, Henry Ford Health, Detroit, MI, USA.
Tae Hwan ParkDepartment of Plastic and Reconstructive Surgery, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Republic of Korea.
Julian PötschkeDepartment of Plastic and Handsurgery, Burn Center, Klinikum St. Georg gGmbH, Leipzig, Germany.
Anthony RossiMemorial Sloan Kettering Cancer Center, 530 East 74th Street, Office 9104, New York, NY, 10021, USA.
Swee T TanGillies McIndoe Research Institute, Wellington, New Zealand.
Luc TéotDepartment of Plastic Surgery, Montpellier University Hospital, Montpellier, France.
Fiona M WoodBurns Service of Western Australia, Fiona Stanley Hospital, Perth Childrens Hospital, University of Western Australia, Crawley, Australia.
Nanze YuDepartment of Plastic and Aesthetic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
Susan GibbsDepartment of Molecular Cell Biology and Immunology, Amsterdam Institute for Infection and Immunity (AII), Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
Frank B Niessen *Department of Plastic, Reconstructive and Hand Surgery, Amsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
Paul P M van Zuijlen *Department of Plastic, Reconstructive and Hand Surgery, Amsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundIntralesional corticosteroid administration (ICA) is a first-line keloid treatment. However, it faces significant variability in current clinical and scientific practice, which hinders comparability of treatment results.

objectivesThe aim of the study was to reach consensus on different aspects of ICA using hypodermic needles in keloids among an international group of dermatologists and plastic surgeons specialized in keloid treatment to provide consensus-based clinical treatment recommendations for all physicians treating keloids.

methodsThe keloid expert panel of 12 dermatologists and 11 plastic surgeons rated 30 statements. Two online e-Delphi rounds were held, both with a response rate of 100%. Fifteen (65%) keloid experts participated in the final consensus meetings. Consensus was defined as ≥ 75% of the participants choosing agree or strongly agree on a 7-point Likert scale.

resultsConsensus was reached on treatment goals, indication for ICA, triamcinolone acetonide (TAC) 40 mg/mL as the preferred corticosteroid administered at a maximum of 80 mg per month and at intervals of 4 weeks, minimizing pain during ICA, the use of 1 mL syringes and 25 or 27 Gauge needles, blanching as endpoint of successful infiltration, caution of not injecting subcutaneously, and the option of making multiple passes in very firm keloids prior to infiltration. Consensus could not be reached on TAC dosing, methods of prior local anesthesia, and location of injection.

conclusionsThis e-Delphi study provides important clinical treatment recommendations on essential aspects of ICA in keloids. By implementing these recommendations, uniformity of ICA in keloid treatment will increase and better treatment results may be achieved.

Indexed as

ConsensusDelphi TechniqueGlucocorticoidsInjections, IntralesionalKeloidTriamcinolone AcetonideAdrenal Cortex HormonesDermatologistsHumansNeedlesSurgery, PlasticTreatment OutcomeAdrenal Cortex HormonesGlucocorticoidsTriamcinolone Acetonide

Identifiers

PMID39298112
PMCPMC11511692

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.