Evidence map›Paper›PMID 39297897›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2024

Osteoporosis screening using QCT-based cutoff value of Hounsfield units in patients with degenerative lumbar diseases.

Da Zou, Xuan He, Zesen Shang, Dan Jin, Weishi Li

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Multi-center validation of automated CT-based L1 vertebral Hounsfield unit.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  2. Article
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  4. Simplified sagittal slice HU measurement as a practical alternative to conventional axial HU in opportunistic osteoporosis screening.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  5. Article
  6. Effects of lumbar degeneration on the global and regional bone mineral density in osteoporotic patients requiring lumbar interbody fusion for degenerative lumbar diseases.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Da Zou *Orthopaedics Department, Peking University Third Hospital, Haidian, Beijing, China.
Xuan He *Orthopaedics Department, Peking University Third Hospital, Haidian, Beijing, China.
Zesen ShangOrthopaedics Department, Peking University Third Hospital, Haidian, Beijing, China.
Dan JinOrthopaedics Department, Peking University Third Hospital, Haidian, Beijing, China.
Weishi LiOrthopaedics Department, Peking University Third Hospital, Haidian, Beijing, China. puh3liweishi@163.com.

Funding

National Natural Science Foundation of China No.82202779
6 · The paper itself

Abstract

purposeIn patients with degenerative lumbar diseases, we aimed to establish the cutoff value of Hounsfield units (HU) for osteoporosis screening on the basis of the relationship between computed tomography (CT) HU value and volume bone mineral density (BMD) measured by quantitative computed tomography (QCT).

methodsA total of 136 patients aged ≥ 50 years with degenerative lumbar diseases were retrospectively included. Their QCT-BMD of L1-2 were recorded, and the CT values of L1-2 were measured with the same CT images of QCT. The degree of bone loss was evaluated with the criteria based on QCT-BMD: cutoff value of 80 mg/cm

resultsThe rate of osteoporosis, osteopenia, normal BMD was 33.8% (46/136), 51.5% (70/136), and 14.7% (20/136), respectively. The Pearson correlation coefficients between CT value and QCT-BMD were over 0.9 (P < 0.05). The cutoff of average CT value of L1-2 was calculated and adjusted to 110HU for osteoporosis and 160HU for osteopenia according the equation: average QCT-BMD of L1-2 = 0.76 ✕ average CT value of L1-2-0.46 (R

conclusionThe CT value is effective in osteoporosis screening, and the QCT-based cutoff value is 110 HU for osteoporosis and 160 HU for osteopenia in the patients with degenerative lumbar disease.

Indexed as

Bone DensityLumbar VertebraeOsteoporosisTomography, X-Ray ComputedAgedAged, 80 and overBone Diseases, MetabolicFemaleHumansIntervertebral Disc DegenerationMaleMiddle AgedRetrospective StudiesDegenerative lumbar diseaseHounsfield unitOsteopeniaOsteoporosisQuantitative computed tomography

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.