Evidence map›Paper›PMID 39297827›Full record

ArticleThe Journal of hand surgery2024

Pain Interference Prior to and 1 Year After Surgery for Adult Traumatic Brachial Plexus Injury.

Christopher J Dy, David M Brogan, Bryan J Loeffler, Steve K Lee, Harvey Chim, Mihir J Desai, Sami H Tuffaha, Yusha Liu, PLANeT Study Group

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of hand surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Development of a Core Outcomes Set for Peripheral Nerve Injury.Journal of hand surgery global online · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christopher J DyDepartment of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, MO. Electronic address: dyc@wustl.edu.
David M BroganDepartment of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, MO.
Bryan J LoefflerAtrium Musculoskeletal Institute, OrthoCarolina, Charlotte, NC.
Steve K LeeDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY.
Harvey ChimDivision of Plastic and Reconstructive Surgery, University of Florida, Gainesville, FL.
Mihir J DesaiDepartment of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN.
Sami H TuffahaDepartment of Plastic and Reconstructive Surgery, Johns Hopkins School of Medicine, Baltimore, MD.
Yusha LiuDepartment of Plastic and Reconstructive Surgery, University of Washington Medical Center, Seattle, WA.
PLANeT Study Group

Funding

Establishing The Validity, Responsiveness, And Appropriateness Of Patient-Reported Outcome Measures For Adult Traumatic Brachial Plexus InjuryR01AR079139 · NIAMS · WASHINGTON UNIVERSITY · PI DY, CHRISTOPHER JOHN · 2021 to 2023
$656k
NIAMS NIH HHS R01 AR079139
6 · The paper itself

Abstract

purposePain after brachial plexus injury (BPI) can be severely debilitating and is poorly understood. We hypothesized that pain interference (PI) ("the extent to which pain hinders engagement in life") would be predicted by depression, anxiety, severity of pain symptoms, and poorer preoperative muscle function.

methodsAmong patients in a prospective multicenter BPI cohort study, 37 completed Patient-Reported Outcomes Measurement Information System (PROMIS) PI questionnaires before and 1 year after surgery. At both times, participants completed anxiety and depression questionnaires and BPI-specific measures of pain symptoms, physical limitations, and emotional recovery. Surgeon-graded muscle testing, injury severity, age at the time of injury, body mass index, and time from injury to surgery were included. We performed a bivariate analysis of predictors for preoperative and 1-year PROMIS PI followed by multivariable regression modeling using stepwise selection and Bayesian Information Criterion to select covariates.

resultsBefore surgery, the mean PROMIS PI score was 60.8 ± 11.0, with moderate correlations between PROMIS PI and depression, as well as between PROMIS PI and functional limitations. At 1 year after surgery, the mean PROMIS PI score was 59.7 ± 9.5. There was no difference in preoperative and 1-year PROMIS PI. There were strong correlations between PROMIS PI and pain symptoms, functional limitations, and emotional aspects of recovery at the 1-year follow-up that remained significant in multivariable regression. There were no notable associations between muscle testing and PI.

conclusionsPain interference remained substantial and elevated in BPI patients 1 year after surgery. We noted strong associations between PI and pain symptoms, functional limitations, and emotional aspects of recovery. These findings demonstrate the persistence of pain as a feature throughout life after BPI and that its treatment should be considered a priority alongside efforts to improve extremity function. TYPE OF STUDY/LEVEL OF EVIDENCE: Prognosis IV.

Indexed as

DepressionAdultAnxietyBrachial PlexusBrachial Plexus NeuropathiesFemaleHumansMaleMiddle AgedPain MeasurementPatient Reported Outcome MeasuresProspective StudiesBrachial plexus injuryneuropathic painpainpain interferenceperipheral nerve injury

Identifiers

PMID39297827
PMCPMC13399483

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.