Evidence map›Paper›PMID 39296884›Full record

ArticlemicroPublication biology2024

Resveratrol natural product inspired compound as a potent neuroprotectant against acute oxidative stress.

Alec Simonson, Akshay Naraine, Samantha Maki, Kristina Nugent, Salvatore Lepore, Ken Dawson-Scully

Abstract read
In one paragraph

Article in microPublication biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alec SimonsonDepartment of Biological Sciences, Florida Atlantic University, Boca Raton, Florida, United States.
Akshay NaraineDepartment of Biological Sciences, Florida Atlantic University, Boca Raton, Florida, United States.
Samantha MakiDepartment of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, Florida, United States.
Kristina NugentDepartment of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, Florida, United States.
Salvatore LeporeDepartment of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, Florida, United States.
Ken Dawson-ScullyDepartment of Biological Sciences, Florida Atlantic University, Boca Raton, Florida, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resveratrol as well as natural products biosynthetically derived from it, have been shown to have protective effects against oxidative stress. However, these compounds possess poor druglike properties. At sub-nanomolar concentrations, a novel compound (RVM-6) inspired by a resveratrol natural product prolongs synaptic viability in neuromuscular junctions in

Identifiers

PMID39296884
PMCPMC11409061

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.