Evidence map›Paper›PMID 39296504›Full record

ArticleFrontiers in nutrition2024

Case report: Carnivore-ketogenic diet for the treatment of inflammatory bowel disease: a case series of 10 patients.

Nicholas G Norwitz, Adrian Soto-Mota

Abstract readCase Reports
In one paragraph

Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Plant and Animal Protein Sources in Inflammatory Bowel Disease: Current Evidence and Clinical Implications.JGH open : an open access journal of gastroenterology and hepatology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nicholas G NorwitzHarvard Medical School, Boston, MA, United States.
Adrian Soto-MotaMetabolic Diseases Research Unit, National Institute for Medical Sciences and Nutrition Salvador Zubiran, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Very-low-carbohydrate diets, including ketogenic and carnivore diets, are gaining popularity for the experimental treatment of a wide range of disorders, including inflammatory bowel disease (IBD). Methods: Participants were recruited through a social media survey. Final inclusion required a histologically confirmed diagnosis of ulcerative colitis (UC) or Crohn's disease that was responsive to treatment with a ketogenic or carnivore diet without medication or with successful medication cessation on the diet. Clinical improvement was measured with the Inflammatory Bowel Disease Questionnaire (IBDQ). Results: We report on 10 cases of IBD responsive to ketogenic, mostly carnivore, diets. Clinical presentations were diverse, including six cases of UC and four of Crohn's disease. Clinical improvements were universal, with clinical improvement scores ranging between 72 and 165 points on the IBDQ. Patients' diets comprised mostly meat, eggs, and animal fats. Patients report their diets are pleasurable, sustainable, and unequivocally enhance their quality of life. Conclusion: Ketogenic and carnivore diets hold promise for the treatment of IBD, including UC and Crohn's disease. These cases are consistent with clinical literature that shows an inverse association between intestinal ketone levels and IBD activity, as well as the therapeutic effects of low residue elimination diets on colonic microbiota metabolism.

Indexed as

carnivore dietCrohn’s diseaseinflammatory bowel diseaseketogenic dietulcerative colitis

Identifiers

PMID39296504
PMCPMC11409203

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.