Evidence map›Paper›PMID 39296471›Full record

ArticleImmunometabolism (Cobham, Surrey)2024

Imaging immunometabolism

Nicole Molnar, Veronika Miskolci

Abstract read
In one paragraph

Article in Immunometabolism (Cobham, Surrey), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Deciphering macrophage molecular responses toFrontiers in microbiology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nicole MolnarDepartment of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers Health, Rutgers University, Newark, NJ, USA.
Veronika MiskolciDepartment of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers Health, Rutgers University, Newark, NJ, USA.

Funding

Metabolic regulation of macrophage-dependent wound healing in vivoR00GM138699 · NIGMS · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI MISKOLCI, VERONIKA · 2023 to 2025
$739k
Metabolic regulation of macrophage-dependent wound healing in vivoK99GM138699 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI MISKOLCI, VERONIKA · 2021 to 2022
$200k
NIGMS NIH HHS K99 GM138699NIGMS NIH HHS R00 GM138699
6 · The paper itself

Abstract

Immunometabolism is a rapidly developing field that holds great promise for diagnostic and therapeutic benefits to human diseases. The field has emerged based on seminal findings from in vitro and ex vivo studies that established the fundamental role of metabolism in immune cell effector functions. Currently, the field is acknowledging the necessity of investigating cellular metabolism within the natural context of biological processes. Examining cells in their native microenvironment is essential not only to reveal cell-intrinsic mechanisms but also to understand how cross-talk between neighboring cells regulates metabolism at the tissue level in a local niche. This necessity is driving innovation and advancement in multiple imaging-based technologies to enable analysis of dynamic intracellular metabolism at the single-cell level, with spatial and temporal resolution. In this review, we tally the currently available imaging-based technologies and explore the emerging methods of Raman and autofluorescence lifetime imaging microscopy, which hold significant potential and offer broad applications in the field of immunometabolism.

Indexed as

enzymatic activity assayFADFLIMimmune cellslifetime imagingNAD(P)Hoptical redox ratioRamanspatial metabolomics

Identifiers

PMID39296471
PMCPMC11406703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.