Evidence map›Paper›PMID 39296470›Full record

ArticleSclerosis2024

Diet-Induced Changes in Functional Disability among People with Multiple Sclerosis: A Secondary Pooled Analysis of Two Randomized Controlled Pilot Trials.

Allison R Groux, Elizabeth S Walker, Farnoosh Shemirani, Jennifer E Lee, Amanda K Irish, Linda M Rubenstein, Linda G Snetselaar, Warren G Darling, Terry L Wahls, Tyler J Titcomb

Abstract read
In one paragraph

Article in Sclerosis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Allison R GrouxDepartment of Internal Medicine, University of Iowa, Iowa City, IA 52340, USA.ORCID 0009-0005-6577-9849
Elizabeth S WalkerDepartment of Internal Medicine, University of Iowa, Iowa City, IA 52340, USA.ORCID 0000-0003-4312-6255
Farnoosh ShemiraniDepartment of Internal Medicine, University of Iowa, Iowa City, IA 52340, USA.
Jennifer E LeeCollege of Nursing, University of Iowa, Iowa City, IA 52340, USA.ORCID 0000-0002-2365-7211
Amanda K IrishDepartment of Emergency Medicine, University of Iowa, Iowa City, IA 52340, USA.ORCID 0009-0006-9122-7869
Linda M RubensteinDepartment of Epidemiology, University of Iowa, Iowa City, IA 52340, USA.
Linda G SnetselaarDepartment of Epidemiology, University of Iowa, Iowa City, IA 52340, USA.
Warren G DarlingDepartment of Health and Human Physiology, University of Iowa, Iowa City, IA 52340, USA.
Terry L WahlsDepartment of Internal Medicine, University of Iowa, Iowa City, IA 52340, USA.ORCID 0000-0001-6059-7994
Tyler J TitcombDepartment of Internal Medicine, University of Iowa, Iowa City, IA 52340, USA.ORCID 0000-0002-8162-4768

Funding

MARC at University of IowaT34GM141143 · NIGMS · UNIVERSITY OF IOWA · PI ADAMS-PHILLIPS, LORI C, FORBES, TORI · 2021 to 2024
$1.5M
NIGMS NIH HHS T34 GM141143
6 · The paper itself

Abstract

Emerging evidence links dietary interventions to favorable multiple sclerosis (MS) outcomes; however, evidence for the efficacy of dietary interventions on functional disability remains sparse. Data from two 12-week, randomized, controlled pilot trials were pooled to investigate the efficacy of a modified Paleolithic diet (Paleo) on functional disability, as assessed by the MS Functional Composite (MSFC), among people diagnosed with MS. Pooled baseline-referenced MSFC scores were calculated from the nine-hole peg test (NHPT), timed 25-foot walk (T25FW), and Paced Auditory Serial Addition Test (PASAT) Z-scores. There was no significant difference in the mean change in MSFC scores between groups (

Indexed as

functional disabilitymodified Paleolithic dietmultiple sclerosismultiple sclerosis functional compositenine-hole peg test

Identifiers

PMID39296470
PMCPMC11410177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.