Evidence map›Paper›PMID 39296440›Full record

ArticleJournal of medicine and life2024

Somatic and germline mutations in endometrial cancer.

Robert Botea, Madalina Piron-Dumitrascu, Tiberiu Augustin Georgescu, Camil Laurentiu Bohiltea, Silviu Cristian Voinea, Valentin Nicolae Varlas, Simona Raluca Iacoban, Nicolae Suciu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicine and life, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Robert BoteaDepartment of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Madalina Piron-DumitrascuDepartment of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Tiberiu Augustin GeorgescuDepartment of Pathology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Camil Laurentiu BohilteaDepartment of Medical Genetics, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Silviu Cristian VoineaDepartment of General Surgery, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Valentin Nicolae VarlasDepartment of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Simona Raluca IacobanDepartment of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Nicolae SuciuDepartment of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometrial cancer is a complex disease influenced by both somatic and germline mutations. While individual mutations in genes such as

Indexed as

Endometrial NeoplasmsGerm-Line MutationAgedClass I Phosphatidylinositol 3-KinasesExome SequencingFemaleHumansMiddle AgedMutationMutL Protein Homolog 1PTEN PhosphohydrolaseClass I Phosphatidylinositol 3-KinasesMLH1 protein, humanMutL Protein Homolog 1PIK3CA protein, humanPTEN PhosphohydrolasePTEN protein, humancancer geneticsEndometrial cancergermline mutationspersonalized medicinesomatic mutationswhole exome sequencing

Identifiers

PMID39296440
PMCPMC11407495

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.