ArticleBiomedical optics express2024
Chromatic cues for the sign of defocus in the peripheral retina.
Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Short-Term Axial Length Effects of Combining Paracentral Collimating Apertures with Near-Peripheral Myopic Defocus for Myopia Control.Journal of clinical medicine · 2026Article
- Subregion-based maximum similarity search registration method for transverse chromatic aberration correction in ultra-widefield scanning laser ophthalmoscopy images.Journal of biomedical optics · 2026Article
- Impact of Myopia Control Spectacles on Retinal Image Contrast.Investigative ophthalmology & visual science · 2026Article
- S-Cone Retinal Pathway Dysfunction in Myopia.Investigative ophthalmology & visual science · 2026Article
- Optical and Visual Diet in Myopia.Investigative ophthalmology & visual science · 2025Review
- Chromatic imaging properties of myopia control spectacle lenses.Biomedical optics express · 2025Article
- Retinal Responses to Short- and Longer-Term Predominant ON or OFF Stimulation in Emmetropes and Myopes.Investigative ophthalmology & visual science · 2025Article
- Quantifying monochromatic and polychromatic optical blur anisotropy in the periphery of myopes and emmetropes using a radial asymmetry metric.Frontiers in medicine · 2025Article
- Visual Quality and Accommodation With Novel Optical Designs for Myopia Control.Translational vision science & technology · 2024Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Detecting optical defocus at the retina is crucial for accurate accommodation and emmetropization. However, the optical characteristics of ocular defocus are not fully understood. To bridge this knowledge gap, we simulated polychromatic retinal image quality by considering both the monochromatic wavefront aberrations and chromatic aberrations of the eye, both in the fovea and the periphery (nasal visual field). Our study revealed two main findings: (1) chromatic and monochromatic aberrations interact to provide a signal to the retina (chromatic optical anisotropy) to discern positive from negative defocus and (2) that chromatic optical anisotropy exhibited notable differences among refractive error groups (myopes, emmetropes and hyperopes). These findings could enhance our understanding of the underlying mechanisms of defocus detection and their subsequent implications for myopia control therapies. Further research is needed to explore the retinal architecture's ability to utilize the optical signals identified in this study.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.