Evidence map›Paper›PMID 39296137›Full record

ArticleHeliyon2024

Non-targeted metabolomics reveals the characteristics of the unique bitterness substances in quinoa.

Junqi Huo, Tingting Feng, Heting Shang, Chen Guo, Tianyu Wu, Mingjuan Chu, Huixin Zhao, Erbin Wu, Hui Li, Shuo Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Junqi HuoHebei North University Hebei Key Laboratory of Analysis and Testing for Quality and Safety of Agricultural Products and Food, Hebei North University, Zhangjiakou, 075000, China.
Tingting FengHebei North University Hebei Key Laboratory of Analysis and Testing for Quality and Safety of Agricultural Products and Food, Hebei North University, Zhangjiakou, 075000, China.
Heting ShangHebei North University Hebei Key Laboratory of Analysis and Testing for Quality and Safety of Agricultural Products and Food, Hebei North University, Zhangjiakou, 075000, China.
Chen GuoHebei North University Hebei Key Laboratory of Analysis and Testing for Quality and Safety of Agricultural Products and Food, Hebei North University, Zhangjiakou, 075000, China.
Tianyu WuHebei North University College of traditional Chinese Medicine, Zhangjiakou, 075000, China.
Mingjuan ChuHebei North University College of traditional Chinese Medicine, Zhangjiakou, 075000, China.
Huixin ZhaoHebei North University College of traditional Chinese Medicine, Zhangjiakou, 075000, China.
Erbin WuZhangjiakou Animal Health Supervision Institute, Zhangjiakou, 075000, China.
Hui LiHebei North University Hebei Key Laboratory of Analysis and Testing for Quality and Safety of Agricultural Products and Food, Hebei North University, Zhangjiakou, 075000, China.
Shuo WangSchool of Medicine, Nankai University, Tianjin, 300350, China.
Dong WeiHebei North University Hebei Key Laboratory of Analysis and Testing for Quality and Safety of Agricultural Products and Food, Hebei North University, Zhangjiakou, 075000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bitterness is a key factor that affects the consumption of quinoa products, even if they are nutritious. In this study, a non-targeted metabolomics approach based on UHPLC-Orbitrap-MS was applied to comprehensively profile the characteristic metabolites of twenty-two quinoas. A total of twenty key metabolites were identified correlated with bitterness, among which, fifteen were triterpenoid saponins. In addition, these metabolites bind to the active site of the human bitter taste receptor and are the main compounds that produce the bitter taste of quinoa. Our results contribute to a deeper understanding of the origin of quinoa bitterness and provide directions for optimizing its flavor to improve market acceptance.

Indexed as

Bitter metabolitesQuinoaSensory analysisUntargeted metabolomics

Identifiers

PMID39296137
PMCPMC11409112

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.