Evidence map›Paper›PMID 39296075›Full record

ArticleHeliyon2024

Single-cell transcriptomics reveals the cellular identity of a novel progenitor population crucial for murine neural tube closure.

Zihao Deng, Marina R Carpinelli, Tariq Butt, Graham W Magor, Peinan Zhao, Kevin R Gillinder, Andrew C Perkins, Stephen M Jane

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zihao DengDepartment of Medicine (Alfred Hospital), School of Translational Medicine, Monash University, 99 Commercial Rd, Melbourne, VIC, 3004, Australia.
Marina R CarpinelliDepartment of Medicine (Alfred Hospital), School of Translational Medicine, Monash University, 99 Commercial Rd, Melbourne, VIC, 3004, Australia.
Tariq ButtDepartment of Medicine (Alfred Hospital), School of Translational Medicine, Monash University, 99 Commercial Rd, Melbourne, VIC, 3004, Australia.
Graham W MagorAustralian Centre for Blood Diseases, School of Translational Medicine, Monash University, 99 Commercial Rd, Melbourne, VIC, 3004, Australia.
Peinan ZhaoDepartment of Medicine (Alfred Hospital), School of Translational Medicine, Monash University, 99 Commercial Rd, Melbourne, VIC, 3004, Australia.
Kevin R GillinderAustralian Centre for Blood Diseases, School of Translational Medicine, Monash University, 99 Commercial Rd, Melbourne, VIC, 3004, Australia.
Andrew C PerkinsAustralian Centre for Blood Diseases, School of Translational Medicine, Monash University, 99 Commercial Rd, Melbourne, VIC, 3004, Australia.
Stephen M JaneDepartment of Medicine (Alfred Hospital), School of Translational Medicine, Monash University, 99 Commercial Rd, Melbourne, VIC, 3004, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural tube closure in vertebrates is achieved through a highly dynamic and coordinated series of morphogenic events involving neuroepithelium, surface ectoderm, and neural plate border. Failure of this process in the caudal region causes spina bifida. Grainyhead-like 3 (GRHL3) is an indispensable transcription factor for neural tube closure as constitutive inactivation of the

Indexed as

Grhl3Neural tube closureNeural tube defectsSingle cell-RNA sequencingTfap2aTfap2c

Identifiers

PMID39296075
PMCPMC11408003

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.