ArticleWorld journal of transplantation2024
Recipient functional status impacts on short and long-term intestinal transplant outcomes in United States adults.
Article in World journal of transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Longitudinal Assessment of Performance Status in US Liver Transplantation: National Trends and Survival Implications.Transplantation direct · 2025Article
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5 authors.
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Abstract
backgroundRecipient functional status prior to transplantation has been found to impact post-transplant outcomes in heart, liver and kidney transplants. However, information on how functional status, before and after transplant impacts post-transplant survival outcomes is lacking.
aimTo investigate the impact of recipient functional status on short and long term intestinal transplant outcomes in United States adults.
methodsWe conducted a retrospective cohort study on 1254 adults who underwent first-time intestinal transplantation from 2005 to 2022. The primary outcome was mortality. Using the Karnofsky Performance Status, functional impairment was categorized as severe, moderate and normal. Analyses were conducted using Kaplan-Meier curves and multivariable Cox regression.
resultsThe median age was 41 years, majority (53.4%) were women. Severe impairment was present in 28.3% of recipients. The median survival time was 906.6 days. The median survival time was 1331 and 560 days for patients with normal and severe functional impairment respectively. Recipients with severe impairment had a 56% higher risk of mortality at one year [Hazard ratio (HR) = 1.56; 95%CI: 1.23-1.98;
conclusionPre- and post-transplant recipient functional status is an important prognostic indicator for short- and long-term intestinal transplant outcomes.
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