Evidence map›Paper›PMID 39295925›Full record

ArticleCase reports in urology2024

Edema of the Scrotum and Penile Shaft: An Uncommon Initial Presentation of Acquired Angioedema With Low C1-Inhibitor.

Meghan V Matheny, Timothy Craig, Joseph Y Clark

Abstract readCase Reports
In one paragraph

Article in Case reports in urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Meghan V MathenySchool of Medicine Penn State University, 500 University Drive, Hershey, Pennsylvania 17033, USA.ORCID https://orcid.org/0000-0003-3981-520X
Timothy CraigSection of Allergy Asthma & Immunology Pennsylvania State University School of Medicine, 500 University Drive, Hershey, Pennsylvania 17033, USA.ORCID https://orcid.org/0000-0002-7774-4855
Joseph Y ClarkDepartment of Urology Pennsylvania State University School of Medicine, USA.ORCID https://orcid.org/0000-0002-3817-4343

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acquired angioedema with low C1-inhibitor (AAE-C1-INH) is a rare disorder characterized by an acquired deficiency in the C1 esterase inhibitor (C1-INH). This case report describes a 79-year-old patient presenting to the emergency department for painless swelling of his scrotum, penile shaft, and left lower and upper extremities with lab values consistent with acquired angioedema without identifiable lymphoreticular or rheumatic disorder on history, exam, or total body PET scan. Proper diagnosis of AAE-C1-INH is essential to prevent life-threatening airway compromise, ensure proper therapy, and exclude lymphoreticular disorders as the etiology of AAE-C1-INH.

Indexed as

acquired angioedemaacquired angioedema with low C1-inhibitorangioedemapenile angioedemascrotum angioedema

Identifiers

PMID39295925
PMCPMC11410412

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.