Evidence map›Paper›PMID 39295868›Full record

ArticleFrontiers in immunology2024

Case report: A clinical report of photodynamic neoadjuvant combined with fluorescent laparoscopic localization robotic surgery for the treatment of patients with advanced colorectal cancer combined with obstruction.

Xiaodong Huang, Xiaowen Han, Weidong Li, Jiayi Zhang, Bin Ma, Yuhan Wang, Zhenyu Yin, Lei Gao, Jianming Shi, Ewetse Paul Maswikiti and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaodong Huang *The Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou, China.
Xiaowen Han *The Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou, China.
Weidong Li *The Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou, China.
Jiayi Zhang *The Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou, China.
Bin MaThe Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou, China.
Yuhan WangThe Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou, China.
Zhenyu YinThe Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou, China.
Lei GaoThe Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou, China.
Jianming ShiThe Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou, China.
Ewetse Paul MaswikitiThe Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou, China.
Hao ChenThe Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of colorectal cancer is relatively high in our country, with the majority of patients being diagnosed at an advanced stage. For individuals with advanced-stage colorectal cancer, conversion or neoadjuvant therapy is frequently necessitated to facilitate surgical intervention and achieve a curative effect. And about 10% to 30% of colon cancer patients are complicated with intestinal obstruction. Surgical intervention remains the primary treatment for managing intestinal obstructions, albeit with a considerable risk of perioperative mortality and an increased likelihood of postoperative complications. PDT, as a neoadjuvant treatment for colon cancer, can shrink the local tumor and relieve obstruction, and is effective in colon cancer combined with obstruction. Robotic surgery has the advantages of high stability and low trauma, and compared with laparoscopic colon cancer surgery, robotic surgery can achieve better results. Fluorescent laparoscopic clarifies the location and size of the tumor lesion, allowing for greater precision when removing colon cancer lesions in robotic surgery. Therefore, in the treatment of colon cancer, PDT can offer an opportunity for surgery after relieving obstruction in patients with obstructive colon cancer. Additionally, when combined with fluorescent laparoscopic robotic colon cancer surgery, it provides a novel treatment approach for patients with obstructive colon cancer. Preoperative photodynamic neoadjuvant therapy combined with robotic colon cancer surgery has not yet been reported. Here, we report a case of colon cancer with obstruction, preoperative TNM stage was T4N1, and the lesion had caused intestinal stenosis. After four sessions of PDT, the patient's intestinal lumen was unobstructed and the lesion had regressed. After evaluation, fluorescent laparoscopic localization and visualization of lymph nodes combined with robotic colon cancer resection were performed. Postoperative pathology showed that the patient's tumor regression grade was grade 1. The patient's tumor was completely resected with good resection effect. No tumor invasion was found on both sides of the resection margin, and the patient did not relapse after surgery.

Indexed as

Colorectal NeoplasmsIntestinal ObstructionLaparoscopyNeoadjuvant TherapyPhotochemotherapyRobotic Surgical ProceduresAgedFemaleHumansMaleMiddle AgedNeoplasm StagingTreatment Outcomecase reportcolon cancerfluorescence laparoscopyneoadjuvant therapyphotodynamic

Identifiers

PMID39295868
PMCPMC11409080

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