Evidence map›Paper›PMID 39295776›Full record

ArticleGut microbiome (Cambridge, England)2022

Dried chicory root improves bowel function, benefits intestinal microbial trophic chains and increases faecal and circulating short chain fatty acids in subjects at risk for type 2 diabetes.

Marie-Luise Puhlmann, Roosa Jokela, Katja Catharina Wilhelmina van Dongen, Thi Phuong Nam Bui, Roland Willem Jan van Hangelbroek, Hauke Smidt, Willem Meindert de Vos, Edith Johanna Maria Feskens

2 registry-linked trialsAbstract read
In one paragraph

Article in Gut microbiome (Cambridge, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05473793 narecruitingnot on this map

The Impact of a Dried Vegetable on Bowel Function and Gut Microbiota in Subjects With Bowel Function Issues

TypeinterventionalSponsorWageningen UniversityRan2022 to 2025Enrolled160ConditionsBowel Function DissatisfactionArmsDried chicory root particles, Placebo
NCT06212817 narecruitingnot on this mapstarted 2024, after this paper: background citation

FiberUP in Clinical Practice: Increasing Preoperative Dietary Fiber Intake in Colorectal Cancer Patients.

TypeinterventionalSponsorWageningen UniversityRan2024 to 2026Enrolled54ConditionsColorectal CancerArmsDietary intervention
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Gut physiology meets microbiome science.Gut microbiome (Cambridge, England) · 2023
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marie-Luise PuhlmannLaboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.ORCID https://orcid.org/0000-0002-8193-1688
Roosa JokelaHuman Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0002-4144-6573
Katja Catharina Wilhelmina van DongenLaboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.ORCID https://orcid.org/0000-0002-0718-4653
Thi Phuong Nam BuiLaboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.ORCID https://orcid.org/0000-0001-5366-5960
Roland Willem Jan van HangelbroekDivision of Human Nutrition and Health, Wageningen University & Research, Wageningen, The Netherlands.ORCID https://orcid.org/0000-0002-0442-5378
Hauke SmidtLaboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.ORCID https://orcid.org/0000-0002-6138-5026
Willem Meindert de VosLaboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.ORCID https://orcid.org/0000-0002-0273-3166
Edith Johanna Maria FeskensDivision of Human Nutrition and Health, Wageningen University & Research, Wageningen, The Netherlands.ORCID https://orcid.org/0000-0001-5819-2488

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the impact of dried chicory root in a randomised, placebo-controlled trial with 55 subjects at risk for type 2 diabetes on bowel function, gut microbiota and its products, and glucose homeostasis. The treatment increased stool softness (+1.1 ± 0.3 units;

Indexed as

BlautiaChicory rootgut microbiotaintrinsic fibreshort-chain fatty acidstype 2 diabetes

Identifiers

PMID39295776
PMCPMC11407914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.